5-Hydroxytryptophol-d₄

Name: 5-Hydroxytryptophol-d 4
Brand: MedChemExpress
SKU: HY-W041019S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W041019S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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5-Hydroxytryptophol-d₄ is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.

For research use only. We do not sell to patients.

5-Hydroxytryptophol-d<sub>4</sub> Chemical Structure

5-Hydroxytryptophol-d₄ Chemical Structure

CAS No. : 66640-87-7

Size	Price	Stock	Quantity
1 mg	USD 180	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 450	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 720	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 5-Hydroxytryptophol-d₄:

5-Hydroxytryptophol In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

5-Hydroxytryptophol-d₄ is the deuterium labeled 5-Hydroxytryptophol. 5-Hydroxytryptophol is a mammalian serotonin metabolite, acting as a marker of acute alcohol consumption.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

181.22

Formula

C₁₀H₇D₄NO₂

CAS No.

66640-87-7

Unlabeled Cas

154-02-9

Appearance

Solid

Color

Light brown to brown

SMILES

OC([2H])([2H])C([2H])([2H])C(C1=C2)=CNC1=CC=C2O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (689.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	5.5182 mL	27.5908 mL	55.1815 mL
5 mM	1.1036 mL	5.5182 mL	11.0363 mL
10 mM	0.5518 mL	2.7591 mL	5.5182 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (274 KB) SDS (251 KB)

COA (253 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

[2]. Beck O, et al. 5-hydroxytryptophol as a marker for recent alcohol intake. Addiction. 2003 Dec;98 Suppl 2:63-72. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	5.5182 mL	27.5908 mL	55.1815 mL	137.9539 mL
	5 mM	1.1036 mL	5.5182 mL	11.0363 mL	27.5908 mL
	10 mM	0.5518 mL	2.7591 mL	5.5182 mL	13.7954 mL
	15 mM	0.3679 mL	1.8394 mL	3.6788 mL	9.1969 mL
	20 mM	0.2759 mL	1.3795 mL	2.7591 mL	6.8977 mL
	25 mM	0.2207 mL	1.1036 mL	2.2073 mL	5.5182 mL
	30 mM	0.1839 mL	0.9197 mL	1.8394 mL	4.5985 mL
	40 mM	0.1380 mL	0.6898 mL	1.3795 mL	3.4488 mL
	50 mM	0.1104 mL	0.5518 mL	1.1036 mL	2.7591 mL
	60 mM	0.0920 mL	0.4598 mL	0.9197 mL	2.2992 mL
	80 mM	0.0690 mL	0.3449 mL	0.6898 mL	1.7244 mL
	100 mM	0.0552 mL	0.2759 mL	0.5518 mL	1.3795 mL