2. Immunology/Inflammation
  3. COX
  4. Etoricoxib-d4

Etoricoxib-d4  (Synonyms: MK-0663-d4; L-791456-d4)

Cat. No.: HY-15321S Purity: 98.93%
COA Handling Instructions

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Etoricoxib-d4 is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.

For research use only. We do not sell to patients.

Etoricoxib-d<sub>4</sub> Chemical Structure

Etoricoxib-d4 Chemical Structure

CAS No. : 1131345-14-6

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1 mg USD 180 In-stock
5 mg USD 540 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Etoricoxib-d4:

Etoricoxib-d4 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Etoricoxib-d4

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Description

Etoricoxib-d4 is a deuterium labeled Etoricoxib. Etoricoxib is a non steroidal anti-inflammatory agent, acting as a selective and orally active COX-2 inhibitor, with IC50s of 1.1 μM and 116 μM for COX-2 and COX-1 in human whole blood.

Molecular Weight

362.87

Formula

C18H11D4ClN2O2S
CAS No.
Unlabeled Cas

202409-33-4
Appearance

Solid

Color

Light yellow to yellow

SMILES

ClC(C=N1)=CC(C2=C([2H])C([2H])=C(S(C)(=O)=O)C([2H])=C2[2H])=C1C3=CN=C(C)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (275.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7558 mL 13.7790 mL 27.5581 mL
5 mM 0.5512 mL 2.7558 mL 5.5116 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7558 mL 13.7790 mL 27.5581 mL 68.8952 mL
5 mM 0.5512 mL 2.7558 mL 5.5116 mL 13.7790 mL
10 mM 0.2756 mL 1.3779 mL 2.7558 mL 6.8895 mL
15 mM 0.1837 mL 0.9186 mL 1.8372 mL 4.5930 mL
20 mM 0.1378 mL 0.6890 mL 1.3779 mL 3.4448 mL
25 mM 0.1102 mL 0.5512 mL 1.1023 mL 2.7558 mL
30 mM 0.0919 mL 0.4593 mL 0.9186 mL 2.2965 mL
40 mM 0.0689 mL 0.3445 mL 0.6890 mL 1.7224 mL
50 mM 0.0551 mL 0.2756 mL 0.5512 mL 1.3779 mL
60 mM 0.0459 mL 0.2297 mL 0.4593 mL 1.1483 mL
80 mM 0.0344 mL 0.1722 mL 0.3445 mL 0.8612 mL
100 mM 0.0276 mL 0.1378 mL 0.2756 mL 0.6890 mL
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Etoricoxib-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Etoricoxib-d41131345-14-6MK-0663-d4L-791456-d4COXCyclooxygenaseInhibitorinhibitorinhibit

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