2. Natural Products
  3. Steroids
  4. Cardiacglycosides

Cardiacglycosides

Cardiacglycosides (32):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1030
    Lanatoside C 17575-22-3 99.83%
    Lanatoside C is a cardiac glycoside, can be used in the treatment of congestive heart failure and cardiac arrhythmia.Lanatoside C has an IC50 of 0.19 μM for dengue virus infection in HuH-7 cells. Lanatoside C can effectively inhibit all four serotypes of dengue virus, flavivirus Kunjin, alphavirus Chikungunya, Sindbis virus and the human enterovirus 71.
    Lanatoside C
  • HY-A0154
    Deslanoside 17598-65-1 99.79%
    Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms, and to control ventricular rate in the treatment of chronic atrial fibrillation. Deslanoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations .
    Deslanoside
  • HY-N8441
    Neriifolin 466-07-9 99.43%
    Neriifolin, a CNS-penetrating cardiac glycoside, is an inhibitor of the Na+, K+-ATPase. Neriifolin can target beclin 1, inhibits the formation of LC3-associated phagosomes and ameliorates experimental autoimmune encephalomyelitis (EAE) development. Neriifolin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells[2.
    Neriifolin
  • HY-N4252
    Periplocymarin 32476-67-8 99.10%
    Periplocymarin, a cardiac glycoside isolated from Periploca sepium and Periploca graeca, is a potential anti-cancer compound.
    Periplocymarin
  • HY-N0817
    Polyphyllin G 76296-75-8
    Polyphyllin G is isolated from the rhizomes of Paris yunnanensis, with antimicrobial and anticancer activity. Polyphyllin G prevents the growth of both Gram-positive and Gram-negative bacteria with minimum inhibitory concentrations (MICs). Polyphyllin G induces apoptosis dependent on the activations of caspase-8, -3, and -9, induces autophagy.
    Polyphyllin G
  • HY-N7669
    Taccalonolide C 117803-96-0 99.13%
    Taccalonolides C is an anti-cancer agent.
    Taccalonolide C
  • HY-N12430
    Marsdenoside A 858360-56-2
    Marsdenoside A (compound 7) is a Marsdenoside isolated from Alocasia genus. Marsdenoside A has a weak growth inhibitory effect on two tumor cell lines, MGC-803 and HT-29, with IC50 >50 μg/mL.
    Marsdenoside A
  • HY-N12437
    Marsdenoside B 858360-57-3
    Marsdenoside B (compound 8) is a Marsdenoside isolated from Alocasia genus. Marsdenoside B inhibits the growth of tumor cell lines MGC-803 and HT-29 with IC50s of 25.6 μg/mL and 32.4 μg/mL, respectively.
    Marsdenoside B
  • HY-16022
    Acetyldigitoxin 1111-39-3
    Acetyldigitoxin (Digitoxin 3'''-Acetate) is a cardiac glycoside. Acetyldigitoxin can come from the leaves of Digitalis species. Acetyldigitoxin reduces the heart rate and can be used for cardiac failure rasearch.
    Acetyldigitoxin
  • HY-111934
    Cymarin 508-77-0
    Cymarin, a cardiac glycoside, potently inhibits the Palytoxin (PTX)-induced K+ release (IC50=0.42 μM). Cymarin reveals an antitumor activity against breast cancer and pancreatic cancer. Cymarin exhibits antifeedant and growth inhibitory effects as crop protectant.
    Cymarin
  • HY-N5093
    Glucodigifucoside 2446-63-1
    Glucodigifucoside, a cardenolide glycoside that could be isolated from the seeds of Digitalis purpurea, exhibits potent cytotoxicity against human renal adenocarcinoma cell line ACHN.
    Glucodigifucoside
  • HY-N6575
    7β-Hydroxybufalin 20143-97-9
    7β-Hydroxybufalin is a bufadienolide. 7β-Hydroxybufalin can be isolated from the venom of Bufo bufo gargarizans. 7β-Hydroxybufalin inhibits α-glucosidase and acetylcholinesterase.
    7β-Hydroxybufalin
  • HY-N3672
    Cynatratoside A 97399-96-7
    Cynatratoside A, an oligoglycoside, is a nature product that could be isolated from the roots of Cynanchum paniculatum.
    Cynatratoside A
  • HY-N10023
    Physalin O 120849-18-5
    Physalin O is a physalin that can be isolated from Physalis angulata. Physalin O shows cytotoxicity to Hep G2 and MCF-7 cancer cells with IC50 values of 31.1 and 11.4 µM, respectively. Physalin O inhibits the production of nitric oxide (NO) and shows anti-inflammatory activities.
    Physalin O
  • HY-N8270
    Physalin H 70241-09-7
    Physalin H is a natural product that can be isolated from Solanum nigrum. Physalin H is an inhibitor of Hedgehog (Hh) signaling and it disrupts GLI1-DNA-complex formation. Physalin H inhibits GLI1 transcription with an IC50 value of 0.7 μM. Physalin H shows cytotoxicity to PANC1 and DU145 cells with IC50 values of 5.7 and 6.8 μM, respectively.
    Physalin H
  • HY-N8679
    Physalin C 27503-33-9
    Physalin C is a natural product that can be found in physalis angulata. Physalin C shows cytotoxic activities against MCF-7 and HepG2 cells.
    Physalin C
  • HY-N10303
    Withangulatin A 120824-03-5
    Withangulatin A is a selective cyclooxygenase-2 (COX-2) inhibitor. Withangulatin A can be isolated from Physalis angulata L. Withangulatin A has anti-tumor, trypanocidal activity and anti-inflammatory function.
    Withangulatin A
  • HY-N7328
    Lanatoside B 17575-21-2
    Lanatoside B is a cardenolide that can be isolated from the leaves of Digitalis lanata.
    Lanatoside B
  • HY-123075
    Odoroside H 18810-25-8
    Odoroside H is a natural cardenolide with anticancer activities.
    Odoroside H
  • HY-N10040
    Poststerone 10162-99-9
    Poststerone is a nature product. Poststerone is a metabolite of insect metamorphosing substances from Cyathula capata.
    Poststerone