2. Immunology/Inflammation Metabolic Enzyme/Protease
  3. COX Lipoxygenase
  4. S-(+)-Marmesin

S-(+)-Marmesin  (Synonyms: (+)-Marmesin; (S)-Marmesin)

Cat. No.: HY-N2176 Purity: 99.04%
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S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

For research use only. We do not sell to patients.

S-(+)-Marmesin Chemical Structure

S-(+)-Marmesin Chemical Structure

CAS No. : 13849-08-6

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5 mg USD 80 In-stock
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100 mg USD 620 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of S-(+)-Marmesin:

S-(+)-Marmesin Related Antibodies

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Description

S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

IC50 & Target[2]

COX-2

 

5-LOX

 

In Vitro

S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism[1]. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

S-(+)-Marmesin Related Antibodies
Molecular Weight

246.26

Formula

C14H14O4
CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

O=C1C=CC2=CC3=C(O[C@H](C(C)(O)C)C3)C=C2O1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 2 mg/mL (8.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0607 mL 20.3037 mL 40.6075 mL
5 mM 0.8121 mL 4.0607 mL 8.1215 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.0607 mL 20.3037 mL 40.6075 mL 101.5187 mL
5 mM 0.8121 mL 4.0607 mL 8.1215 mL 20.3037 mL
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S-(+)-Marmesin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-(+)-Marmesin13849-08-6(+)-Marmesin (S)-MarmesinCOXLipoxygenaseCyclooxygenaseLOXInhibitorinhibitorinhibit

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