2. Anti-infection
  3. HCV
  4. Sofosbuvir-d6

Sofosbuvir-d6  (Synonyms: PSI-7977-d6; GS-7977-d6)

Cat. No.: HY-15005S1 Purity: 98.35%
COA Handling Instructions

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Sofosbuvir-d6 is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

For research use only. We do not sell to patients.

Sofosbuvir-d<sub>6</sub> Chemical Structure

Sofosbuvir-d6 Chemical Structure

CAS No. : 1868135-06-1

Size Price Stock Quantity
1 mg USD 420 In-stock
5 mg USD 1350 In-stock
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50 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Other Forms of Sofosbuvir-d6:

Sofosbuvir-d6 Related Antibodies

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Description

Sofosbuvir-d6 is the deuterium labeled Sofosbuvir. Sofosbuvir (PSI-7977) is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.

Molecular Weight

535.49

Formula

C22H23D6FN3O9P
CAS No.
Unlabeled Cas

1190307-88-0
Appearance

Solid

Color

White to off-white

SMILES

O=C1N([C@H]2[C@]([C@H](O)[C@@H](CO[P@](OC3=CC=CC=C3)(N[C@@H](C)C(OC(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=O)O2)(C)F)C=CC(N1)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (93.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 25 mg/mL (46.69 mM; ultrasonic and warming and heat to 50°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8674 mL 9.3372 mL 18.6745 mL
5 mM 0.3735 mL 1.8674 mL 3.7349 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.35%

COA (261 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 1.8674 mL 9.3372 mL 18.6745 mL 46.6862 mL
5 mM 0.3735 mL 1.8674 mL 3.7349 mL 9.3372 mL
10 mM 0.1867 mL 0.9337 mL 1.8674 mL 4.6686 mL
15 mM 0.1245 mL 0.6225 mL 1.2450 mL 3.1124 mL
20 mM 0.0934 mL 0.4669 mL 0.9337 mL 2.3343 mL
25 mM 0.0747 mL 0.3735 mL 0.7470 mL 1.8674 mL
30 mM 0.0622 mL 0.3112 mL 0.6225 mL 1.5562 mL
40 mM 0.0467 mL 0.2334 mL 0.4669 mL 1.1672 mL
DMSO 50 mM 0.0373 mL 0.1867 mL 0.3735 mL 0.9337 mL
60 mM 0.0311 mL 0.1556 mL 0.3112 mL 0.7781 mL
80 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.5836 mL
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Sofosbuvir-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sofosbuvir-d61868135-06-1PSI-7977-d6GS-7977-d6HCVHepatitis C virusInhibitorinhibitorinhibit

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