2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. FOXO

FOXO

Forkhead box O

 

FOXO Related Products (4):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-153347
    JY-2
    		99.75%
    JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity.
    JY-2
  • HY-15449
    Kaempferide
    		Agonist 99.35%
    Kaempferide is an orally active flavonol isolated from Hippophae rhamnoides L. Kaempferide has anticancer, anti-inflammatory, antioxidant, antidiabetic, antiobesity, antihypertensive, and neuroprotective activities. Kaempferide induces apoptosis. Kaempferide promotes osteogenesis through antioxidants and can be used in osteoporosis research.
    Kaempferide
  • HY-101035
    LOM612
    		98.68%
    LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells.
    LOM612
  • HY-153617
    FOXO1-IN-3
    		99.05%
    FOXO1-IN-3 is a highly-selective and orally active FOXO1 inhibitor. FOXO1-IN-3 reduces hepatic glucose production in mice. FOXO1-IN-3 improves insulin sensitivity and glucose control in db/db mice without causing weight gain.
    FOXO1-IN-3