2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Nuclear Hormone Receptor 4A/NR4A

Nuclear Hormone Receptor 4A/NR4A

Nerve Growth Factor IB-like Receptor

 

Nuclear Hormone Receptor 4A/NR4A Related Products (24):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-115923
    Nur77 modulator 2
    Nur77 modulator 2, a Nur77 modulator (Kd of 0.35 μM), is a potent and orally active inflammation inhibitor. Nur77 modulator 2 modulates the colocalization of Nur77 at mitochondria.
    Nur77 modulator 2
  • HY-155490
    Nur77 antagonist 1
    		Antagonist
    Nur77 antagonist 1(Compound ja) is a selective Nur77 antagonist(KDSPRNur77 = 91 nM). Nur77 antagonist 1 induces cancer cell apoptosis. ja displays excellent antitumor against triple-negative breast cancer (TNBC) cells.
    Nur77 antagonist 1
  • HY-149608
    Nurr1 agonist 5
    		Agonist
    Nurr1 agonist 5 (compound 5o) is a neuroprotective transcription factor Nurr1 agonist with a Kd of 0.5 μM and an EC50 of 3 μM.
    Nurr1 agonist 5
  • HY-B1322AS1
    Amodiaquine-d10 hydrochloride
    		Agonist
    Amodiaquine-d10 hydrochloride is deuterated labeled Amodiaquine (HY-B1322A). Amodiaquine (Amodiaquin), a 4-aminoquinoline class of antimalarial agent, is a potent and orally active histamine N-methyltransferase inhibitor. Amodiaquine is also a Nurr1 agonist and specifically binds to Nurr1-LBD (ligand binding domain) with an EC50 of ~20 μM. Anti-inflammatory effect.
    Amodiaquine-d<sub>10</sub> hydrochloride