2. GPCR/G Protein
  3. GLP Receptor GCGR
  4. Bamadutide

Bamadutide  (Synonyms: SAR425899)

Cat. No.: HY-P10018 Purity: 99.96%
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Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor agonist. Bamadutide (SAR425899) improves postprandial glucose control by significantly enhancing β-cell function and slowing glucose absorption rate in vivo. Bamadutide (SAR425899)can be used for type 2 diabetes research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Bamadutide Chemical Structure

Bamadutide Chemical Structure

CAS No. : 1596343-09-7

Size Price Stock Quantity
5 mg USD 290 In-stock
10 mg USD 460 In-stock
25 mg USD 910 In-stock
50 mg USD 1450 In-stock
100 mg USD 2300 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Bamadutide Related Antibodies

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Description

Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor agonist. Bamadutide (SAR425899) improves postprandial glucose control by significantly enhancing β-cell function and slowing glucose absorption rate in vivo. Bamadutide (SAR425899)can be used for type 2 diabetes research[1].

Molecular Weight

4439.93

Formula

C200H313N51O63
CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

Sequence

His-(d-Ser)-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-{N6-(N-(1-oxohexadecyl)-Ggu)-Lys}-Glu-Ser-Lys-Ala-Ala-Gln-Asp-Phe-Ile-Glu-Trp-Leu-Lys-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Sequence Shortening

H-{d-Ser}-QGTFTSDLSKQ-{N6-(N-(1-oxohexadecyl)-Ggu)-Lys}-ESKAAQDFIEWLKAGGPSSGAPPPS-NH2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (22.52 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.2252 mL 1.1261 mL 2.2523 mL
5 mM 0.0450 mL 0.2252 mL 0.4505 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.2252 mL 1.1261 mL 2.2523 mL 5.6307 mL
5 mM 0.0450 mL 0.2252 mL 0.4505 mL 1.1261 mL
10 mM 0.0225 mL 0.1126 mL 0.2252 mL 0.5631 mL
15 mM 0.0150 mL 0.0751 mL 0.1502 mL 0.3754 mL
20 mM 0.0113 mL 0.0563 mL 0.1126 mL 0.2815 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Bamadutide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bamadutide1596343-09-7SAR425899SAR 425899SAR-425899GLP ReceptorGCGRGlucagon Receptor?Glucagonmetabolic diseaseobesitytype 2 diabetesInhibitorinhibitorinhibit

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