Transcription initiation factor IIE subunit beta

Definition:

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.

References:

[1]. M G Peterson, et al. Structure and functional properties of human general transcription factor IIE. Nature. 1991 Dec 5;354(6352):369-73. [Content Brief]

[2]. H Sumimoto, et al. Conserved sequence motifs in the small subunit of human general transcription factor TFIIE. Nature. 1991 Dec 5;354(6352):401-4. [Content Brief]

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