Transmembrane protein 9B

Definition:

Enhances production of pro-inflammatory cytokines induced by TNF, IL1B, and TLR ligands. Has a role in TNF activation of both the NF-kappaB and MAPK pathways.

References:

[1]. Francis Dodeller, et al. The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways. J Biol Chem. 2008 Aug 1;283(31):21487-94. [Content Brief]

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