1. Metabolic Enzyme/Protease
  2. Cathepsin
  3. Cathepsin K inhibitor 4

Cathepsin K inhibitor 4 is a potent carbohydrazide Cathepsin K inhibitor with IC50s of 13 nM, 269 nM, 296 nM for human, rat, mouse Cathepsin K, respectively.

For research use only. We do not sell to patients.

Cathepsin K inhibitor 4 Chemical Structure

Cathepsin K inhibitor 4 Chemical Structure

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Description

Cathepsin K inhibitor 4 is a potent carbohydrazide Cathepsin K inhibitor with IC50s of 13 nM, 269 nM, 296 nM for human, rat, mouse Cathepsin K, respectively[1].

IC50 & Target

IC50: 13 nM (Cathepsin K), 38 nM (Cathepsin B), 8.9 nM (Cathepsin L), 792 nM (Cathepsin S) and 3.2 nM (Cathepsin F)[1]

Molecular Weight

697.82

Formula

C35H51N7O8

Unlabeled CAS

Sequence

Boc-Phe-Leu-{NHNH-CO-NHNH}-Leu-{Z}

Sequence Shortening

Boc-FL-{NHNH-CO-NHNH}-L-{Z}

SMILES

O=C(N[C@@H](CC(C)C)C(NNC(NNC([C@H](CC(C)C)NC(C(CC1=CC=CC=C1)NC(OC(C)(C)C)=O)=O)=O)=O)=O)OCC2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cathepsin K inhibitor 4
Cat. No.:
HY-P10061
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