2. Anti-infection Metabolic Enzyme/Protease
  3. SARS-CoV Ser/Thr Protease
  4. Debrisoquin hydroiodide

Debrisoquin hydroiodide  (Synonyms: Debrisoquine hydroiodide; Isocaramidine hydroiodide; Ro 5-3307/1 hydroiodide)

Cat. No.: HY-W195509 Purity: 99.84%
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Debrisoquin (hydroiodide) is the hydrochloride form of Debrisoquin (HY-B1624). Debrisoquin is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner. Debrisoquin can be used for antiviral research.

For research use only. We do not sell to patients.

Debrisoquin hydroiodide Chemical Structure

Debrisoquin hydroiodide Chemical Structure

CAS No. : 1052540-65-4

Size Price Stock Quantity
5 mg USD 50 In-stock
10 mg USD 75 In-stock
25 mg USD 128 In-stock
50 mg USD 192 In-stock
100 mg USD 287 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Debrisoquin hydroiodide Related Antibodies

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Description

Debrisoquin (hydroiodide) is the hydrochloride form of Debrisoquin (HY-B1624). Debrisoquin is a TMPRSS2 inhibitors that inhibits SARS-CoV-2 entry into human lung cell line by a TMPRSS2-depedent manner. Debrisoquin can be used for antiviral research[1].

Molecular Weight

303.14

Formula

C10H14IN3
CAS No.
Unlabeled CAS

Appearance

Solid

Color

Off-white to light yellow

SMILES

N=C(N1CC2=C(CC1)C=CC=C2)N.I
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 175 mg/mL (577.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2988 mL 16.4940 mL 32.9881 mL
5 mM 0.6598 mL 3.2988 mL 6.5976 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2988 mL 16.4940 mL 32.9881 mL 82.4701 mL
5 mM 0.6598 mL 3.2988 mL 6.5976 mL 16.4940 mL
10 mM 0.3299 mL 1.6494 mL 3.2988 mL 8.2470 mL
15 mM 0.2199 mL 1.0996 mL 2.1992 mL 5.4980 mL
20 mM 0.1649 mL 0.8247 mL 1.6494 mL 4.1235 mL
25 mM 0.1320 mL 0.6598 mL 1.3195 mL 3.2988 mL
30 mM 0.1100 mL 0.5498 mL 1.0996 mL 2.7490 mL
40 mM 0.0825 mL 0.4124 mL 0.8247 mL 2.0618 mL
50 mM 0.0660 mL 0.3299 mL 0.6598 mL 1.6494 mL
60 mM 0.0550 mL 0.2749 mL 0.5498 mL 1.3745 mL
80 mM 0.0412 mL 0.2062 mL 0.4124 mL 1.0309 mL
100 mM 0.0330 mL 0.1649 mL 0.3299 mL 0.8247 mL
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Debrisoquin hydroiodide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Debrisoquin hydroiodide1052540-65-4Debrisoquine hydroiodideIsocaramidine hydroiodideRo 5-3307/1 hydroiodideSARS-CoVSer/Thr ProteaseSARS coronavirusSerine proteasesSerine endopeptidasesThreonine proteasesinfectionCalu-3 cellshuman lung cell lineTMPRSS2 inhibitorsInhibitorinhibitorinhibit

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