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  3. Isotope-Labeled Compounds
  4. DL-dithiothreitol-d6

DL-dithiothreitol-d6  (Synonyms: DTT-d6)

Cat. No.: HY-15917S2 Purity: ≥99.0%
COA Handling Instructions

Molarity Calculator

DL-dithiothreitol-d6 is the deuterium labeled DL-dithiothreitol[1]. DL-dithiothreitol (DTT) is a reducing agent. DL-dithiothreitol forms a stable six-membered ring with an internal disulfide bond once oxidized[2].

For research use only. We do not sell to patients.

DL-dithiothreitol-d<sub>6</sub> Chemical Structure

DL-dithiothreitol-d6 Chemical Structure

CAS No. : 850153-85-4

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1 mg USD 85 In-stock
5 mg USD 210 In-stock
10 mg USD 340 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of DL-dithiothreitol-d6:

DL-dithiothreitol-d6 Related Antibodies

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Description

DL-dithiothreitol-d6 is the deuterium labeled DL-dithiothreitol[1]. DL-dithiothreitol (DTT) is a reducing agent. DL-dithiothreitol forms a stable six-membered ring with an internal disulfide bond once oxidized[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DL-dithiothreitol-d6 Related Antibodies
Molecular Weight

160.29

Formula

C4H4D6O2S2
CAS No.
Unlabeled CAS

3483-12-3
Appearance

Solid

Color

White to off-white

SMILES

SC([2H])([2H])[C@](O)([2H])[C@@](O)([2H])C([2H])([2H])S
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (623.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 6.2387 mL 31.1935 mL 62.3869 mL
5 mM 1.2477 mL 6.2387 mL 12.4774 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

COA (254 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 6.2387 mL 31.1935 mL 62.3869 mL 155.9673 mL
5 mM 1.2477 mL 6.2387 mL 12.4774 mL 31.1935 mL
10 mM 0.6239 mL 3.1193 mL 6.2387 mL 15.5967 mL
15 mM 0.4159 mL 2.0796 mL 4.1591 mL 10.3978 mL
20 mM 0.3119 mL 1.5597 mL 3.1193 mL 7.7984 mL
25 mM 0.2495 mL 1.2477 mL 2.4955 mL 6.2387 mL
30 mM 0.2080 mL 1.0398 mL 2.0796 mL 5.1989 mL
40 mM 0.1560 mL 0.7798 mL 1.5597 mL 3.8992 mL
50 mM 0.1248 mL 0.6239 mL 1.2477 mL 3.1193 mL
60 mM 0.1040 mL 0.5199 mL 1.0398 mL 2.5995 mL
80 mM 0.0780 mL 0.3899 mL 0.7798 mL 1.9496 mL
100 mM 0.0624 mL 0.3119 mL 0.6239 mL 1.5597 mL
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DL-dithiothreitol-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DL-dithiothreitol-d6850153-85-4DTT-d6Isotope-Labeled CompoundsInhibitorinhibitorinhibit

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