DL-threo-3-Hydroxyaspartic acid

Name: DL-threo-3-Hydroxyaspartic acid
Brand: MedChemExpress
SKU: HY-100801A
Rating: 4.5 (1 reviews)

Cat. No.: HY-100801A Purity: 99.77%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

DL-threo-3-Hydroxyaspartic acid is a glutamate uptake inhibitor that can block glutamate transport in cannulated sprague dawley rat.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

DL-threo-3-Hydroxyaspartic acid Chemical Structure

CAS No. : 4294-45-5

Size	Price	Stock	Quantity
25 mg	USD 261	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 418	In-stock	Estimated Time of Arrival: December 31
100 mg		Get quote
200 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of DL-threo-3-Hydroxyaspartic acid:

L-threo-3-Hydroxyaspartic acid Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

DL-threo-3-Hydroxyaspartic acid is a glutamate uptake inhibitor that can block glutamate transport in cannulated sprague dawley rat^[1]^[2].

Molecular Weight

149.10

Formula

C₄H₇NO₅

CAS No.

4294-45-5

Unlabeled Cas

Appearance

Solid

Color

White to off-white

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 16.67 mg/mL (111.80 mM; ultrasonic and adjust pH to 12 with 1 M NaOH)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.7069 mL	33.5345 mL	67.0691 mL
5 mM	1.3414 mL	6.7069 mL	13.4138 mL
10 mM	0.6707 mL	3.3535 mL	6.7069 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.77%

Select Batch:

Data Sheet (271 KB) SDS (393 KB)

COA (248 KB) HNMR (444 KB) RP-HPLC (204 KB) MS (80 KB)

Handling Instructions (2659 KB)

References

[1]. A Klegeris,et al. Regulation of glutamate in cultures of human monocytic THP-1 and astrocytoma U-373 MG cells.J Neuroimmunol.1997 Sep;78(1-2):152-61. [Content Brief]

[2]. Jessica Darman, et al. Viral-induced spinal motor neuron death is non-cell-autonomous and involves glutamate excitotoxicity.J Neurosci. 2004 Aug 25;24(34):7566-75. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.7069 mL	33.5345 mL	67.0691 mL	167.6727 mL
	5 mM	1.3414 mL	6.7069 mL	13.4138 mL	33.5345 mL
	10 mM	0.6707 mL	3.3535 mL	6.7069 mL	16.7673 mL
	15 mM	0.4471 mL	2.2356 mL	4.4713 mL	11.1782 mL
	20 mM	0.3353 mL	1.6767 mL	3.3535 mL	8.3836 mL
	25 mM	0.2683 mL	1.3414 mL	2.6828 mL	6.7069 mL
	30 mM	0.2236 mL	1.1178 mL	2.2356 mL	5.5891 mL
	40 mM	0.1677 mL	0.8384 mL	1.6767 mL	4.1918 mL
	50 mM	0.1341 mL	0.6707 mL	1.3414 mL	3.3535 mL
	60 mM	0.1118 mL	0.5589 mL	1.1178 mL	2.7945 mL
	80 mM	0.0838 mL	0.4192 mL	0.8384 mL	2.0959 mL
	100 mM	0.0671 mL	0.3353 mL	0.6707 mL	1.6767 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.