2. Metabolic Enzyme/Protease
  3. Dipeptidyl Peptidase
  4. DPP-8/9 probe-1

DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively)..

For research use only. We do not sell to patients.

DPP-8/9 probe-1 Chemical Structure

DPP-8/9 probe-1 Chemical Structure

CAS No. : 3020859-80-4

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DPP-8/9 probe-1 Related Antibodies

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Description

DPP-8/9 probe-1 (compound 20) is a fluorescent probe targeting Dipeptidyl Peptidase DPP8/9, which can be selectively labeled and visualized in vitro by fluorescence microscopy Active DPP8/9. DPP-8/9 probe-1 contains a nitrobenzoxadiazole (NBD) tag and has high affinity and selectivity for DPP8/9 over related S9 family members (IC50 of 210 nM and 15 nM, respectively).[9][1].

IC50 & Target

DPP-8

210 nM (IC50, [1])

DPP-9

15 nM (IC50, [1])

DPP-4

.44 μM (IC50, [1])

In Vitro

DPP-8/9 probe-1 (compound 20) (10 μM; 30 min) significantly stains and visualizes DPP-8/9 in THP cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

DPP-8/9 probe-1 Related Antibodies

Immunofluorescence[1]

Cell Line: THP-1 monocytes
Concentration: 0.5 μM, 1 μM, 2 μM, 10 μM
Incubation Time: 30 min
Result: Lower concentrations (0.5 μM, 1 μM and 2 μM) can not be sufficient for in-cell staining
Sta
Molecular Weight

637.66

Formula

C31H36FN7O7
CAS No.
Unlabeled CAS

SMILES

O=C(CN[C@@]1(C2)C[C@H]3C[C@@](C[C@@H]2C3)(NC(OCCOCCNC4=CC=C([N+]([O-])=O)C5=NON=C54)=O)C1)N(C6)CC7=C6C=CC(F)=C7
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DPP-8/9 probe-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DPP-8/9 probe-13020859-80-4Dipeptidyl PeptidaseDPPBiotinChemical toolsDipeptidyl peptidase 8Dipeptidyl peptidase 9FluorescenceProbeInhibitorinhibitorinhibit

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