2. Apoptosis
  3. Caspase
  4. Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone 

Cat. No.: HY-P4900
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Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy.

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Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone Chemical Structure

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone Chemical Structure

CAS No. : 1926163-65-6

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Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone Related Antibodies

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Description

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone is a cell-permeable, non-toxic inhibitor that binds irreversibly to activated caspase-3 in apoptotic cells. The fluorescence intensity can be measured by flow cytometry, microwell plate reader, or fluorescence microscopy[1].

IC50 & Target

Caspase 3

 

Molecular Weight

892.83

Formula

C43H45FN4O16
CAS No.
Unlabeled CAS

Sequence

{Fluorescein-6-carbonyl}-{Asp(OMe)}-{Glu(OMe)}-Val-{dl-Asp(OMe)}-{Fluoromethylketone}
Sequence Shortening

{Fluorescein-6-carbonyl}-{Asp(OMe)}-{Glu(OMe)}-V-{dl-Asp(OMe)}-{Fluoromethylketone}
SMILES

O=C1OC2(C3=CC=C(O)C=C3OC4=CC(O)=CC=C42)C5=CC(C(N[C@@H](CC(OC)=O)C(N[C@@H](CCC(OC)=O)C(N[C@@H](C(C)C)C(NC(C(CF)=O)CC(OC)=O)=O)=O)=O)=O)=CC=C51
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Fluorescein-6-carbonyl-Asp(OMe)-Glu(OMe)-Val-DL-Asp(OMe)-fluoromethylketone1926163-65-6CaspaseCaspase-3 InhibitorApoptosisInhibitorinhibitorinhibit

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