2. Gene
  3. UBE2H - ubiquitin conjugating enzyme E2 H Gene

UBE2H - ubiquitin conjugating enzyme E2 H Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Homo sapiens

Also known as GID3; UBC8; UBCH; UBCH2; E2-20K

Gene ID: 7328 | Gene type: protein coding

About UBE2H

Cytogenetic location: 7q32.2 Genomic coordinates (GRCh38): 7:129,830,732-129,952,960 (from NCBI)

This gene has 10 transcripts (splice variants), 214 orthologues and 24 paralogues. Ubiquitous expression in heart (RPKM 38.0), adrenal (RPKM 36.4) and 25 other tissues.

Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating Enzyme family. The encoded protein sequence is 100% identical to the mouse homolog and 98% identical to the frog and zebrafish homologs. Three alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq, Feb 2011]

UBE2H Products(3)

mRNA Protein Name
NM_001202498.2 NP_001189427.1 ubiquitin-conjugating enzyme E2 H isoform 3
NM_003344.4 NP_003335.1 ubiquitin-conjugating enzyme E2 H isoform 1
NM_182697.3 NP_874356.1 ubiquitin-conjugating enzyme E2 H isoform 2

UBE2H Protein Structure

UQ_con

UQ_con: Ubiquitin-conjugating enzyme (29 - 144)

  • 0
  • 100
  • 183 a.a.
Protein Preferred Names Protein Names

ubiquitin-conjugating enzyme E2 H

(E3-independent) E2 ubiquitin-conjugating enzyme H

Recombinant UBE2H Proteins

Cat. No. Product Name Accession Purity
HY-P71402 UBE2H Protein, Human (GST) P62256 (M1-L183) ≥95%

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15348 UBE2H Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris UBE2H VGNC VGNC:48054
Rattus norvegicus UBE2H RGD RGD:2319288
Macaca mulatta UBE2H VGNC VGNC:78696
Mus musculus UBE2H MGD MGI:104632
Bos taurus UBE2H VGNC VGNC:36583
Others UBE2H NCBI