2. GPCR/G Protein
  3. GPR35
  4. GPR35 agonist 3

GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system.

For research use only. We do not sell to patients.

GPR35 agonist 3 Chemical Structure

GPR35 agonist 3 Chemical Structure

CAS No. : 123021-85-2

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5 mg USD 120 In-stock
10 mg USD 190 In-stock
25 mg USD 390 In-stock
50 mg USD 625 In-stock
100 mg USD 998 In-stock
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Based on 1 publication(s) in Google Scholar

GPR35 agonist 3 Related Antibodies

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Description

GPR35 agonist 3 is a synthetic GPR35 agonist with an EC50value of 1.4 μM. GPR35 agonist 3 can be used for the research of various diseases, such as gastric cancer, type 2 diabetes, cardiovascular diseases, immune system and peripheral nervous system[1].

IC50 & Target

EC50: 1.4 μM (GPR35)[1].
Ki: 0.0508 μM (GPR35)[1].
IC50: 0.349 μM (GPR35)[1].
In Vitro

GPR35 agonist 3 shows GPR35 agonist potency with an EC50 value of 1.4 μM[1].
GPR35 agonist 3 has affinity and potency for GPR35 with values of 0.0508μM (Ki) and 0.349 μM (IC50)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

GPR35 agonist 3 Related Antibodies
Molecular Weight

279.27

Formula

C12H9NO5S
CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

O=C(O)COC1=CC=C(/C=C(SC(N2)=O)\C2=O)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (447.60 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5808 mL 17.9038 mL 35.8076 mL
5 mM 0.7162 mL 3.5808 mL 7.1615 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5808 mL 17.9038 mL 35.8076 mL 89.5191 mL
5 mM 0.7162 mL 3.5808 mL 7.1615 mL 17.9038 mL
10 mM 0.3581 mL 1.7904 mL 3.5808 mL 8.9519 mL
15 mM 0.2387 mL 1.1936 mL 2.3872 mL 5.9679 mL
20 mM 0.1790 mL 0.8952 mL 1.7904 mL 4.4760 mL
25 mM 0.1432 mL 0.7162 mL 1.4323 mL 3.5808 mL
30 mM 0.1194 mL 0.5968 mL 1.1936 mL 2.9840 mL
40 mM 0.0895 mL 0.4476 mL 0.8952 mL 2.2380 mL
50 mM 0.0716 mL 0.3581 mL 0.7162 mL 1.7904 mL
60 mM 0.0597 mL 0.2984 mL 0.5968 mL 1.4920 mL
80 mM 0.0448 mL 0.2238 mL 0.4476 mL 1.1190 mL
100 mM 0.0358 mL 0.1790 mL 0.3581 mL 0.8952 mL
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GPR35 agonist 3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GPR35 agonist 3123021-85-2GPR35G Protein-Coupled Receptor 35agonistgastric cancertype 2 diabetescardiovascular diseasesimmune systemperipheral nervous systemInhibitorinhibitorinhibit

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GPR35 agonist 3
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