(Rac)-Juvenile Hormone III-d₃

Name: (Rac)-Juvenile Hormone III-d 3
Brand: MedChemExpress
SKU: HY-N7240S
Rating: 4.5 (1 reviews)

Cat. No.: HY-N7240S: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Juvenile Hormone III-d₃ is the deuterium labeled Juvenile Hormone III[1].

For research use only. We do not sell to patients.

(Rac)-Juvenile Hormone III-d<sub>3</sub> Chemical Structure

(Rac)-Juvenile Hormone III-d₃ Chemical Structure

CAS No. : 951116-89-5

Size	Price	Stock	Quantity
2.5 mg	USD 950	In-stock	Estimated Time of Arrival: December 31

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Based on 1 publication(s) in Google Scholar

Other Forms of (Rac)-Juvenile Hormone III-d₃:

(Rac)-Juvenile hormone III In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Juvenile Hormone III-d₃ is the deuterium labeled Juvenile Hormone III[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

269.39

Formula

C₁₆H₂₃D₃O₃

CAS No.

951116-89-5

Unlabeled Cas

24198-95-6

Appearance

Oil

Color

Colorless to light yellow

SMILES

[2H]C([2H])([2H])OC(/C=C(C)/CC/C=C(C)/CCC1C(C)(O1)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMF : ≥ 14 mg/mL (51.97 mM)

Ethanol : ≥ 12 mg/mL (44.55 mM)

DMSO : ≥ 10 mg/mL (37.12 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF:PBS(pH7.2) (1:2) : ≥ 0.3 mg/mL (1.11 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7121 mL	18.5604 mL	37.1209 mL
5 mM	0.7424 mL	3.7121 mL	7.4242 mL
10 mM	0.3712 mL	1.8560 mL	3.7121 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥97.0%

Select Batch:

Data Sheet (266 KB) SDS (251 KB)

COA (242 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMF:PBS(pH7.2) (1:2) / DMSO / Ethanol / DMF	1 mM	3.7121 mL	18.5605 mL	37.1209 mL	92.8023 mL
DMSO / Ethanol / DMF	5 mM	0.7424 mL	3.7121 mL	7.4242 mL	18.5605 mL
	10 mM	0.3712 mL	1.8560 mL	3.7121 mL	9.2802 mL
	15 mM	0.2475 mL	1.2374 mL	2.4747 mL	6.1868 mL
	20 mM	0.1856 mL	0.9280 mL	1.8560 mL	4.6401 mL
	25 mM	0.1485 mL	0.7424 mL	1.4848 mL	3.7121 mL
	30 mM	0.1237 mL	0.6187 mL	1.2374 mL	3.0934 mL
Ethanol / DMF	40 mM	0.0928 mL	0.4640 mL	0.9280 mL	2.3201 mL
DMF	50 mM	0.0742 mL	0.3712 mL	0.7424 mL	1.8560 mL