L-α-Phenyl-glycine-d₅

Name: L-α-Phenyl-glycine-d 5
Brand: MedChemExpress
SKU: HY-W017406S
Rating: 4.5 (1 reviews)

Cat. No.: HY-W017406S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

L-α-Phenyl-glycine-d₅ is the deuterium labeled L-α-Phenyl-glycine.

For research use only. We do not sell to patients.

L-α-Phenyl-glycine-d<sub>5</sub> Chemical Structure

L-α-Phenyl-glycine-d₅ Chemical Structure

CAS No. : 1246820-68-7

Size	Price	Stock	Quantity
1 mg	USD 85	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
10 mg		Get quote
50 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of L-α-Phenyl-glycine-d₅:

H-Phg-OH In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

L-α-Phenyl-glycine-d₅ is the deuterium labeled L-α-Phenyl-glycine.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

156.19

Formula

C₈H₄D₅NO₂

CAS No.

1246820-68-7

Unlabeled Cas

2935-35-5

Appearance

Solid

Color

White to off-white

SMILES

OC([C@H](C1=C([2H])C([2H])=C([2H])C([2H])=C1[2H])N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H2O : 33.33 mg/mL (213.39 mM; ultrasonic and adjust pH to 12 with NaOH)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.4025 mL	32.0123 mL	64.0246 mL
5 mM	1.2805 mL	6.4025 mL	12.8049 mL
10 mM	0.6402 mL	3.2012 mL	6.4025 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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Dosing volume
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (274 KB) SDS (252 KB)

COA (252 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H2O	1 mM	6.4025 mL	32.0123 mL	64.0246 mL	160.0615 mL
	5 mM	1.2805 mL	6.4025 mL	12.8049 mL	32.0123 mL
	10 mM	0.6402 mL	3.2012 mL	6.4025 mL	16.0061 mL
	15 mM	0.4268 mL	2.1342 mL	4.2683 mL	10.6708 mL
	20 mM	0.3201 mL	1.6006 mL	3.2012 mL	8.0031 mL
	25 mM	0.2561 mL	1.2805 mL	2.5610 mL	6.4025 mL
	30 mM	0.2134 mL	1.0671 mL	2.1342 mL	5.3354 mL
	40 mM	0.1601 mL	0.8003 mL	1.6006 mL	4.0015 mL
	50 mM	0.1280 mL	0.6402 mL	1.2805 mL	3.2012 mL
	60 mM	0.1067 mL	0.5335 mL	1.0671 mL	2.6677 mL
	80 mM	0.0800 mL	0.4002 mL	0.8003 mL	2.0008 mL
	100 mM	0.0640 mL	0.3201 mL	0.6402 mL	1.6006 mL