1. Metabolic Enzyme/Protease
  2. Cathepsin
  3. Cathepsin K inhibitor 6

Cathepsin K inhibitor 6 (compound 19) is an inhibitor of cathepsin K (Cat K) with an IC50 of 17 nM. Cathepsin K inhibitor 6 also has inhibitory effects on other isoforms, with IC50s of 0.05 μM (Cat L) and 0.3 μM (Cat B), respectively.

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Cathepsin K inhibitor 6 Chemical Structure

Cathepsin K inhibitor 6 Chemical Structure

CAS No. : 325775-42-6

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Description

Cathepsin K inhibitor 6 (compound 19) is an inhibitor of cathepsin K (Cat K) with an IC50 of 17 nM. Cathepsin K inhibitor 6 also has inhibitory effects on other isoforms, with IC50s of 0.05 μM (Cat L) and 0.3 μM (Cat B), respectively[1].

IC50 & Target[1]

cathepsin L

0.05 μM (IC50)

Cathepsin B

0.3 μM (IC50)

cathepsin K

17 nM (IC50)

Molecular Weight

251.30

Formula

C11H13N3O2S

CAS No.
Unlabeled Cas

Appearance

Solid

Color

White to off-white

SMILES

N#CN1CC(C1)CNS(=O)(C2=CC=CC=C2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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Cathepsin K inhibitor 6 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cathepsin K inhibitor 6
Cat. No.:
HY-147774
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