Propofol-d₁₇ β-D-glucuronide

Name: Propofol-d 17 β-D-glucuronide
Brand: MedChemExpress
SKU: HY-118774S
Rating: 4.5 (1 reviews)

Cat. No.: HY-118774S Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Propofol-d₁₇ β-D-glucuronide is the deuterium labeled Propofol β-D-glucuronide[1].

For research use only. We do not sell to patients.

Propofol-d<sub>17</sub> β-D-glucuronide Chemical Structure

Propofol-d₁₇ β-D-glucuronide Chemical Structure

CAS No. : 1683581-05-6

Size	Price	Stock	Quantity
1 mg	USD 980	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 2550	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 4300	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

or Bulk Inquiry

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Propofol-d₁₇ β-D-glucuronide:

Propofol β-D-glucuronide In-stock

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Propofol-d₁₇ β-D-glucuronide is the deuterium labeled Propofol β-D-glucuronide[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

371.50

Formula

C₁₈H₉D₁₇O₇

CAS No.

1683581-05-6

Unlabeled Cas

114991-26-3

Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])C(C([2H])=C([2H])C([2H])=C1C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=C1O[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

Ethanol : ≥ 30 mg/mL (80.75 mM)

DMF : ≥ 30 mg/mL (80.75 mM)

DMSO : ≥ 30 mg/mL (80.75 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

PBS (pH 7.2) : ≥ 10 mg/mL (26.92 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6918 mL	13.4590 mL	26.9179 mL
5 mM	0.5384 mL	2.6918 mL	5.3836 mL
10 mM	0.2692 mL	1.3459 mL	2.6918 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (281 KB) SDS (252 KB)

COA (263 KB) HNMR (127 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

PBS (pH 7.2) / Ethanol / DMF / DMSO	1 mM	2.6918 mL	13.4590 mL	26.9179 mL	67.2948 mL
	5 mM	0.5384 mL	2.6918 mL	5.3836 mL	13.4590 mL
	10 mM	0.2692 mL	1.3459 mL	2.6918 mL	6.7295 mL
	15 mM	0.1795 mL	0.8973 mL	1.7945 mL	4.4863 mL
	20 mM	0.1346 mL	0.6729 mL	1.3459 mL	3.3647 mL
	25 mM	0.1077 mL	0.5384 mL	1.0767 mL	2.6918 mL
Ethanol / DMF / DMSO	30 mM	0.0897 mL	0.4486 mL	0.8973 mL	2.2432 mL
	40 mM	0.0673 mL	0.3365 mL	0.6729 mL	1.6824 mL
	50 mM	0.0538 mL	0.2692 mL	0.5384 mL	1.3459 mL
	60 mM	0.0449 mL	0.2243 mL	0.4486 mL	1.1216 mL
	80 mM	0.0336 mL	0.1682 mL	0.3365 mL	0.8412 mL