1. Others
  2. Isotope-Labeled Compounds
  3. (Rac)-Bendroflumethiazide-d5

(Rac)-Bendroflumethiazide-d5 is the deuterium labeled (Rac)-Bendroflumethiazide[1].

For research use only. We do not sell to patients.

(Rac)-Bendroflumethiazide-d<sub>5</sub> Chemical Structure

(Rac)-Bendroflumethiazide-d5 Chemical Structure

CAS No. : 1330183-13-5

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1 mg USD 100 In-stock
5 mg USD 360 In-stock
10 mg USD 580 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

(Rac)-Bendroflumethiazide-d5 is the deuterium labeled (Rac)-Bendroflumethiazide[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

426.45

Formula

C15H9D5F3N3O4S2

CAS No.
Unlabeled Cas

73-48-3

Appearance

Solid

Color

White to off-white

SMILES

O=S1(C2=CC(S(N)(=O)=O)=C(C(F)(F)F)C=C2NC(N1)CC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (586.24 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3449 mL 11.7247 mL 23.4494 mL
5 mM 0.4690 mL 2.3449 mL 4.6899 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.3449 mL 11.7247 mL 23.4494 mL 58.6235 mL
5 mM 0.4690 mL 2.3449 mL 4.6899 mL 11.7247 mL
10 mM 0.2345 mL 1.1725 mL 2.3449 mL 5.8624 mL
15 mM 0.1563 mL 0.7816 mL 1.5633 mL 3.9082 mL
20 mM 0.1172 mL 0.5862 mL 1.1725 mL 2.9312 mL
25 mM 0.0938 mL 0.4690 mL 0.9380 mL 2.3449 mL
30 mM 0.0782 mL 0.3908 mL 0.7816 mL 1.9541 mL
40 mM 0.0586 mL 0.2931 mL 0.5862 mL 1.4656 mL
50 mM 0.0469 mL 0.2345 mL 0.4690 mL 1.1725 mL
60 mM 0.0391 mL 0.1954 mL 0.3908 mL 0.9771 mL
80 mM 0.0293 mL 0.1466 mL 0.2931 mL 0.7328 mL
100 mM 0.0234 mL 0.1172 mL 0.2345 mL 0.5862 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(Rac)-Bendroflumethiazide-d5
Cat. No.:
HY-B1363S
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