2. GPCR/G Protein Neuronal Signaling
  3. Melatonin Receptor
  4. Ramelteon-d3

Ramelteon-d3  (Synonyms: TAK-375-d3)

Cat. No.: HY-A0014S1 Purity: ≥99.0%
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Ramelteon-d3 is a deuterium-labelled Ramelteon (HY-A0014).

For research use only. We do not sell to patients.

Ramelteon-d<sub>3</sub> Chemical Structure

Ramelteon-d3 Chemical Structure

CAS No. : 1432057-38-9

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1 mg USD 590 In-stock
5 mg USD 1480 In-stock
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Based on 1 publication(s) in Google Scholar

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Ramelteon-d3 Related Antibodies

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Description

Ramelteon-d3 is a deuterium-labelled Ramelteon (HY-A0014).

Molecular Weight

262.36

Formula

C16H18D3NO2
CAS No.
Unlabeled Cas

196597-26-9
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])CC(NCC[C@H]1C2=C(CC1)C=CC3=C2CCO3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (190.58 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8116 mL 19.0578 mL 38.1156 mL
5 mM 0.7623 mL 3.8116 mL 7.6231 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.8116 mL 19.0578 mL 38.1156 mL 95.2889 mL
5 mM 0.7623 mL 3.8116 mL 7.6231 mL 19.0578 mL
10 mM 0.3812 mL 1.9058 mL 3.8116 mL 9.5289 mL
15 mM 0.2541 mL 1.2705 mL 2.5410 mL 6.3526 mL
20 mM 0.1906 mL 0.9529 mL 1.9058 mL 4.7644 mL
25 mM 0.1525 mL 0.7623 mL 1.5246 mL 3.8116 mL
30 mM 0.1271 mL 0.6353 mL 1.2705 mL 3.1763 mL
40 mM 0.0953 mL 0.4764 mL 0.9529 mL 2.3822 mL
50 mM 0.0762 mL 0.3812 mL 0.7623 mL 1.9058 mL
60 mM 0.0635 mL 0.3176 mL 0.6353 mL 1.5881 mL
80 mM 0.0476 mL 0.2382 mL 0.4764 mL 1.1911 mL
100 mM 0.0381 mL 0.1906 mL 0.3812 mL 0.9529 mL
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Ramelteon-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ramelteon-d31432057-38-9TAK-375-d3Melatonin ReceptorRamelteon;TAK-375Inhibitorinhibitorinhibit

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