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Clinical Compound Library

Cat. No.: HY-L026

New drug development is a time-consuming and high-cost process. Drug repurposing (also called drug repositioning, reprofiling or re‑tasking) offers various advantages over developing an entirely new drug for a given indication, such as lower risk and less investment. Clinical drugs have confirmed bioactivities, clear mechanisms and high safety that are suitable for drug repurposing.

MCE owns a unique collection of 2511 clinical compounds that refer to various research areas including anti-cancer, anti-infection, anti-inflammation, nervous disease. Those compounds are of detailed information on clinical development status, research area, targets, etc.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

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Description & Advantages

•   A unique collection of 2511 clinical compounds for high throughput screening (HTS) and high content screening (HCS).

•   Research areas include anticancer, anti-infection, anti inflammation, nervous disease, and more.

•   A useful tool for drug repurposing.

•   Currently in clinical stage, some are withdrawn or terminated.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 2511 clinical compounds supplied as pre-dissolved Solutions or Solid
Solution: 2446 compounds supplied in 10 mM solution, 53 compounds supplied in 2 mM solution, 12 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

VEGFR (59)

EGFR (56)

PI3K (53)

CDK (42)

HIV (36)

iGluR (33)

JAK (33)

PPAR (33)

FGFR (31)

FLT3 (30)

Akt (28)

mTOR (28)

PDGFR (28)

HDAC (27)

CCR (22)

HSP (22)

Btk (21)

HCV (20)

c-Kit (19)

CXCR (19)

mGluR (19)

MMP (19)

nAChR (18)

PARP (18)

c-Fms (16)

COX (16)

mAChR (16)

MEK (15)

HBV (14)

Raf (14)

Src (14)

ERK (13)

FAK (12)

FXR (11)

STAT (11)

Syk (11)

Related Service
Recommendation
Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
  •  YES
Contact Us for Customization

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    Product Name:
    Clinical Compound Library
    Cat. No.:
    HY-L026
    Quantity:
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack