1. One-stop Drug Screening
  2. Screening Libraries
  3. Bioactive Compound Series
  4. According to Signaling Pathway or Protein Family
  5. Potassium Channel Compound Library
Potassium Channel Compound Library

Cat. No.: HY-L119

Potassium channels are the most widely distributed type of ion channel and are found in virtually all living organisms. There are four major classes of K channels: voltage-gated potassium channel, calcium-activated potassium channel, inwardly rectifying potassium channel and tandem pore domain potassium channel. There is growing evidence that dysfunction in potassium channels correlates with several diseases, such as chronic hypertension, diabetes, hypercholesterolemia and atherosclerosis, etc.

MCE Potassium Channel Compound Library consists of 215 potassium channel inhibitor and activators, which is a useful tool to discover drugs for cardiovascular diseases and potassium channel research.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, and 2 mM for compounds with solubility between 2 mM and 10 mM.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
- +

Compound Screening Libraries

Top Publications Citing Use of MedChemExpress (MCE) Products

Publications Citing Use of MedChemExpress (MCE) Products

  • Biological Activity
  • Product Details
  • Documentation
  • Composition

Description & Advantages

•   A unique collection of 215 potassium channel inhibitors and activators for high throughput screening (HTS) and high content screening (HCS).

•   A useful tool for the discovery of cardiovascular diseases drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

Product Details

Formulation:

A collection of 215 otassium channel inhibitors and activators supplied as pre-dissolved Solutions or Solid
Solution: 214 compounds supplied in 10 mM solution, 1 compounds supplied in 2 mM solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice

Related Service
Recommendation
Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
  •  YES
Contact Us for Customization

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

     

Container *

    Remarks

    Inquiry Information

    Product Name:
    Potassium Channel Compound Library
    Cat. No.:
    HY-L119
    Quantity:
    MCE Japan Authorized Agent:

    Request SDF File

    Please enter your email address. We will send your requested SDF file to you as soon as possible.

    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack