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SARS-CoV-2-IN-81

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-161261
    SARS-CoV-2-IN-81

    		AAK1 SARS-CoV Infection
    SARS-CoV-2-IN-81 (compound 12e) is a potent AAK1 inhibitor with an IC50 value of 9.38 nM. SARS-CoV-2-IN-81 shows anti-viral property against SARS-CoV-2. SARS-CoV-2-IN-81 attenuates AAK1-induced phosphorylation of AP2M1 threonine 156 and disrupts the direct interaction between AP2M1 and ACE2, ultimately inhibiting SARS-CoV-2 infection .
    <em>SARS-CoV-2-IN-81</em>

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