2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. Sulfo-LC-SPDP sodium

Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

Sulfo-LC-SPDP sodium Chemical Structure

Sulfo-LC-SPDP sodium Chemical Structure

CAS No. : 169751-10-4

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Based on 1 publication(s) in Google Scholar

Other Forms of Sulfo-LC-SPDP sodium:

Sulfo-LC-SPDP sodium Related Antibodies

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Description

Sulfo-LC-SPDP sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Disulfide Cleavable Linker

 

Cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Sulfo-LC-SPDP sodium Related Antibodies
Molecular Weight

527.57

Formula

C18H22N3NaO8S3
CAS No.
Unlabeled CAS

Appearance

Solid

Color

White to off-white

SMILES

O=C(ON1C(C(S(=O)(O[Na])=O)CC1=O)=O)CCCCCNC(CCSSC2=NC=CC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Purity & Documentation
References
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Sulfo-LC-SPDP sodium Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sulfo-LC-SPDP169751-10-4ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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