1. Screening Libraries
  2. Virtual Screening
  3. Asinex Macrocycles for RNA Library
Asinex Macrocycles for RNA Library

Cat. No.: HY-L0116V

Macrocycles are promising scaffolds for the design of novel RNA targeting molecules. This collection of macrocycles for RNA consists of very diverse, drug-like molecules which incorporate certain known RNA-recognition elements (e.g. nucleobase ring systems and analogs) distributed within macrocyclic rings or peripheral fragments. As macrocyclic molecules tend to be larger than traditional screening molecules, it is vital to carefully assess and control their physicochemical properties. All macrocycles have been tested for aqueous and DMSO solubility with cutoffs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4); PAMPA permeability has also been tested for representative set of macrocycles.

  • Chinese National Compound Library
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Compound Screening Libraries

Product Details

•   All macrocycles for RNA incorporate certain known RNA-recognition elements (e.g. nucleobase ring systems and analogs) distributed within macrocyclic rings or peripheral fragments.

•   A useful tool for finding new RNA-targeted hits.

•   All macrocycles have been tested for aqueous and DMSO solubility with cutoffs applied at 10 mM in DMSO and 50 µM in PBS (pH 7.4); PAMPA permeability has also been tested for representative set of macrocycles.

•   All compounds can be readily followed with analogues either from stock or from new syntheses.

•   Databases and compounds are provided by Asinex.

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  •  Concentration
  •  Form (Solid or Solution)
  •  YES
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Asinex Macrocycles for RNA Library
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HY-L0116V
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  • Chinese National Compound Library