1. Screening Libraries
  2. Virtual Screening
  3. Asinex PPI Pre-Plated Library
Asinex PPI Pre-Plated Library

Cat. No.: HY-L0119V

Protein protein interactions (PPI) have pivotal roles in life processes. The studies showed that aberrant PPI are associated with various diseases. However, the design of modulators targeting PPI still faces tremendous challenges, such the difficult PPI interfaces for the drug design, lack of ligands reference, lack of guidance rules for the PPI modulators development and high-resolution PPI proteins structures.

The PPI Library comprises molecules of various sizes, frameworks, and shapes ranging from fragment-like entities to macrocyclic derivatives designed as secondary structure mimetics or as epitope mimetics. The designs cover β-turn / loop mimetics and α-helix mimetics. Since helices present at the interface in 62% of all protein-protein interactions. This library focused on designs including mimics with the substitution geometry of an a-helices, as well as designs that mimic the location of “hot-spot” side chains in helix-mediated PPIs.

  • Chinese National Compound Library
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Compound Screening Libraries

Product Details

•   A unique collection of 3,253 PPI compounds from Asinex.

•   A useful tool for the discovery of PPI inhibitor.

•   Various sizes, frameworks, and shapes ranging from fragment-like entities to macrocyclic derivatives designed as secondary structure mimetics or as epitope mimetics.

•   All compounds can be readily followed with analogues either from stock or from new syntheses.

•   Databases and compounds are provided by Asinex.

Compound Customization
  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
  •  YES
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Product Name:
Asinex PPI Pre-Plated Library
Cat. No.:
HY-L0119V
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  • Chinese National Compound Library