Antibody-drug conjugates/ADCs Related
Cell Cycle/DNA Damage
Membrane Transporter/Ion Channel
Protein Tyrosine Kinase/RTK
Vitamin D Related
Biochemical assay reagents
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PathWay: Protein Tyrosine Kinase/RTK
PRT062607(P505-15; PRT-2607; BIIB-057) is a highly specific and potent inhibitor of Syk with IC50 of 1-2 nM; >80-fold selective for Syk than Fgr, Lyn, FAK, Pyk2 and Zap70.
Stauprimide is a small molecule that increases the efficiency of the directed differentiation of mouse and human ESCs; interacts with NME2 and inhibits its nuclear localization.
PathWay: GPCR/G protein
Target: Endothelin Receptor
BQ-788 is a potent and selective endothelin receptor subtype B (ETB) antagonist with IC50 of 1.2 nM(inhibits 125I-labeled endothelin 1 (ET-1) binding to ETB receptors on human Girardi heart cells).
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