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Avibactam

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-132987
    Avibactam tomilopil
    2 Publications Verification

    ARX-1796; AV-006

    Beta-lactamase Bacterial Infection
    Avibactam tomilopil (ARX-1796, AV-006), an Avibactam proagent, is an orally bioavailable β-lactamase inhibitor. Avibactam has a spectrum of inhibition of class A and C β-lactamases, including ESBLs, AmpC and Klebsiella pneumoniae carbapenemase (KPC) enzymes .
    <em>Avibactam</em> tomilopil
  • HY-14879A
    Avibactam sodium
    Maximum Cited Publications
    56 Publications Verification

    NXL-104

    Beta-lactamase Bacterial Antibiotic Infection
    Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
    <em>Avibactam</em> sodium
  • HY-14879B
    Avibactam sodium hydrate
    Maximum Cited Publications
    56 Publications Verification

    NXL-104 hydrate

    Beta-lactamase Bacterial Antibiotic Infection
    Avibactam sodium (NXL-104) hydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
    <em>Avibactam</em> sodium hydrate
  • HY-14879
    Avibactam free acid
    Maximum Cited Publications
    56 Publications Verification

    NXL-104 free acid

    Beta-lactamase Bacterial Antibiotic Infection
    Avibactam (NXL-104) free acid is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
    <em>Avibactam</em> free acid
  • HY-14879C

    NXL-104 dihydrate

    Avibactam sodium (NXL-104) dihydrate is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively .
    <em>Avibactam</em> sodium dihydrate
  • HY-139745

    Beta-lactamase Bacterial Infection
    FPI-1523 sodium, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 sodium also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 sodium exhibits considerable antimicrobial activity .
    FPI-1523 sodium
  • HY-139745A

    Beta-lactamase Bacterial Infection
    FPI-1523, a derivative of Avibactam, is a potent β-lactamase inhibitor, with Kds of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. FPI-1523 also inhibits PBP2, with an IC50 of 3.2 μM. FPI-1523 exhibits considerable antimicrobial activity .
    FPI-1523

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