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  3. Castor oil

Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites.

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Castor oil Chemical Structure

Castor oil Chemical Structure

CAS No. : 8001-79-4

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Based on 2 publication(s) in Google Scholar

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Description

Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites[1][2].

In Vitro

Castor oil (CO) is an inedible vegetable oil that has been employed extensively as a bioresource material for the synthesis of biodegradable polymers, cosmetics, lubricants, biofuels, coatings and adhesives. Castor oil is used in medicine, pharmaceuticals and biorefineries, due to its versatile chemistry[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Castor oil is a natural triglyceride which has a laxative effect and induces labor in pregnant females. When given castor oil, wild-type mice respond with a strong diarrhea, starting about 30 min after application. The laxative effect lasts for about 2 h[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

89.91

CAS No.
Appearance

Oil

Color

Colorless to light yellow

SMILES

[Castor oil]

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Pure form -20°C 3 years
4°C 2 years
Solvent & Solubility
In Vitro: 

Ethanol : 4.55 mg/mL (50.61 mM; Need ultrasonic)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

References
Animal Administration
[1]

Mice are used to measure the laxative effects of Castor oil and starved 16 h before the experiments. On the day of the experiment, mice are treated with the Castor oil, and the bottom of the cages is covered with white tissue paper. The weight of shapeless and watery stools is determined hourly[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol 1 mM 11.1222 mL 55.6112 mL 111.2223 mL 278.0558 mL
5 mM 2.2244 mL 11.1222 mL 22.2445 mL 55.6112 mL
10 mM 1.1122 mL 5.5611 mL 11.1222 mL 27.8056 mL
15 mM 0.7415 mL 3.7074 mL 7.4148 mL 18.5371 mL
20 mM 0.5561 mL 2.7806 mL 5.5611 mL 13.9028 mL
25 mM 0.4449 mL 2.2244 mL 4.4489 mL 11.1222 mL
30 mM 0.3707 mL 1.8537 mL 3.7074 mL 9.2685 mL
40 mM 0.2781 mL 1.3903 mL 2.7806 mL 6.9514 mL
50 mM 0.2224 mL 1.1122 mL 2.2244 mL 5.5611 mL
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Castor oil Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Castor oil
Cat. No.:
HY-107799
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