1. Cyclandelate

Cyclandelate  (Synonyms: 3,5,5-Trimethylcyclohexyl mandelate)

Cat. No.: HY-B1170 Purity: 99.45%
COA Handling Instructions

Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis, and Raynaud's disease.

For research use only. We do not sell to patients.

Cyclandelate Chemical Structure

Cyclandelate Chemical Structure

CAS No. : 456-59-7

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
500 mg USD 50 In-stock
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5 g   Get quote  

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Description

Cyclandelate is a vasodilator used in the treatment of claudication, arteriosclerosis, and Raynaud's disease. It is also used to treat nighttime leg cramps, and has been investigated for its effect against migraine.

Molecular Weight

276.37

Formula

C17H24O3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(OC1CC(C)(C)CC(C)C1)C(O)C2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 44 mg/mL (159.21 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6183 mL 18.0917 mL 36.1834 mL
5 mM 0.7237 mL 3.6183 mL 7.2367 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6183 mL 18.0917 mL 36.1834 mL 90.4584 mL
5 mM 0.7237 mL 3.6183 mL 7.2367 mL 18.0917 mL
10 mM 0.3618 mL 1.8092 mL 3.6183 mL 9.0458 mL
15 mM 0.2412 mL 1.2061 mL 2.4122 mL 6.0306 mL
20 mM 0.1809 mL 0.9046 mL 1.8092 mL 4.5229 mL
25 mM 0.1447 mL 0.7237 mL 1.4473 mL 3.6183 mL
30 mM 0.1206 mL 0.6031 mL 1.2061 mL 3.0153 mL
40 mM 0.0905 mL 0.4523 mL 0.9046 mL 2.2615 mL
50 mM 0.0724 mL 0.3618 mL 0.7237 mL 1.8092 mL
60 mM 0.0603 mL 0.3015 mL 0.6031 mL 1.5076 mL
80 mM 0.0452 mL 0.2261 mL 0.4523 mL 1.1307 mL
100 mM 0.0362 mL 0.1809 mL 0.3618 mL 0.9046 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Cyclandelate
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HY-B1170
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