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Caspofungin diacetate Data Sheet
| Product Name: | Caspofungin diacetate |
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| CAS No.: | 179463-17-3 | |
| Cat. No.: | HY-17006 | |
| MWt: | 1213.42 | |
| Formula: | C56H96N10O19 | |
| Purity : | >98% | |
| Solubility: | H2O : ≥ 100 mg/mL (82.41 mM); DMSO : 100 mg/mL (82.41 mM; Need ultrasonic) | |
| Mechanisms: | Target: Cancer Infection | |
| Biological Activity: | ||
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Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2].
In Vivo:Caspofungin diacetate (1-8 mg/kg; i.p.; daily, for 7 days) is able to penetrate the CNS in mice and achieve concentrations that result in the reduction of Candida burden in the brain[1]. Caspofungin diacetate (0.41-41 μM; i.p.; for 5 weeks; male C57BL/6 mice) is a safe antifungal agent at vitreal concentrations of 0.41 to 4.1 μM in mice[2]. |
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