1. GPCR/G Protein Neuronal Signaling
  2. Opioid Receptor
  3. Deltorphin 2

Deltorphin 2  (Synonyms: [D-Ala2]-Deltorphin II)

Cat. No.: HY-P1013
Handling Instructions

Deltorphin 2 is a selective peptide agonist for the δ opioid receptor.

For research use only. We do not sell to patients.

Deltorphin 2 Chemical Structure

Deltorphin 2 Chemical Structure

CAS No. : 122752-16-3

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Other Forms of Deltorphin 2:

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Description

Deltorphin 2 is a selective peptide agonist for the δ opioid receptor.

IC50 & Target

δ opioid receptor[1]

In Vitro

Deltorphin 2 ([D-Ala2]-Deltorphin II) is enzymatically stable, amphibian heptapeptides that has a high affinity and selectivity for delta-opioid receptor. Deltorphin 2 is the most selective natural delta opioid receptor agonist[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

782.88

Formula

C38H54N8O10

CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

Y-{d-Ala}-FEVVG-NH2

SMILES

O=C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(NCC(N)=O)=O)=O)=O)[C@@H](NC([C@@H](C)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O)CC2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 7.5 mg/mL (9.58 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2773 mL 6.3867 mL 12.7733 mL
5 mM 0.2555 mL 1.2773 mL 2.5547 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.2773 mL 6.3867 mL 12.7733 mL 31.9334 mL
5 mM 0.2555 mL 1.2773 mL 2.5547 mL 6.3867 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Deltorphin 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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