1. Cell Cycle/DNA Damage
    Cytoskeleton
  2. PAK

FRAX1036 

Cat. No.: HY-19538 Purity: >98.0%
Handling Instructions

FRAX1036 is a novel ATP-competitive small molecule inhibitor of group I p21-activated Kinases (PAKs).

For research use only. We do not sell to patients.
FRAX1036 Chemical Structure

FRAX1036 Chemical Structure

CAS No. : 1432908-05-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 219 In-stock
1 mg USD 96 In-stock
5 mg USD 192 In-stock
10 mg USD 324 In-stock
50 mg USD 1320 In-stock
100 mg USD 2280 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

FRAX1036 is a novel ATP-competitive small molecule inhibitor of group I p21-activated Kinases (PAKs). Target: PAK in vitro: FRAX1036 demonstrates sensitivity of PAK1-amplified breast cancer cells to this compound. FRAX1036 combines with docetaxel to alter signaling to microtubule regulators and induce apoptotic markers in luminal breast cancer lines.[1]

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 1.9303 mL 9.6516 mL 19.3032 mL
5 mM 0.3861 mL 1.9303 mL 3.8606 mL
10 mM 0.1930 mL 0.9652 mL 1.9303 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

518.05

Formula

C₂₈H₃₂ClN₇O

CAS No.

1432908-05-8

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: 5.3 mg/mL (Need warming)

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
FRAX1036
Cat. No.:
HY-19538
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