2. Stem Cell/Wnt
  3. Smo
  4. Halcinonide

Halcinonide  (Synonyms: SQ-18566)

Cat. No.: HY-B0877 Purity: 99.56%
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Halcinonide (SQ-18566) is a high potency corticosteroid used topically in the treatment of certain skin conditions.

For research use only. We do not sell to patients.

Halcinonide Chemical Structure

Halcinonide Chemical Structure

CAS No. : 3093-35-4

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Solid + Solvent
10 mM * 1 mL in DMSO
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Solution
10 mM * 1 mL in DMSO USD 55 In-stock
Solid
5 mg USD 32 In-stock
10 mg USD 50 In-stock
50 mg USD 90 In-stock
100 mg USD 160 In-stock
200 mg USD 290 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

Halcinonide (SQ-18566) is a high potency corticosteroid used topically in the treatment of certain skin conditions.

Molecular Weight

454.96

Formula

C24H32ClFO5
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

C[C@@]12[C@@]3(C(CCl)=O)[C@@](OC(C)(O3)C)([H])C[C@@]1([H])[C@]4([H])CCC5=CC(CC[C@]5(C)[C@@]4(F)[C@@H](O)C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 48 mg/mL (105.50 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1980 mL 10.9900 mL 21.9800 mL
5 mM 0.4396 mL 2.1980 mL 4.3960 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1980 mL 10.9900 mL 21.9800 mL 54.9499 mL
5 mM 0.4396 mL 2.1980 mL 4.3960 mL 10.9900 mL
10 mM 0.2198 mL 1.0990 mL 2.1980 mL 5.4950 mL
15 mM 0.1465 mL 0.7327 mL 1.4653 mL 3.6633 mL
20 mM 0.1099 mL 0.5495 mL 1.0990 mL 2.7475 mL
25 mM 0.0879 mL 0.4396 mL 0.8792 mL 2.1980 mL
30 mM 0.0733 mL 0.3663 mL 0.7327 mL 1.8317 mL
40 mM 0.0549 mL 0.2747 mL 0.5495 mL 1.3737 mL
50 mM 0.0440 mL 0.2198 mL 0.4396 mL 1.0990 mL
60 mM 0.0366 mL 0.1832 mL 0.3663 mL 0.9158 mL
80 mM 0.0275 mL 0.1374 mL 0.2747 mL 0.6869 mL
100 mM 0.0220 mL 0.1099 mL 0.2198 mL 0.5495 mL
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Halcinonide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Halcinonide3093-35-4SQ-18566SQ18566SQ 18566SmoSmoothenedInhibitorinhibitorinhibit

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