IRAK inhibitor 4 (trans)

Cat. No.: HY-13278A Purity: 99.02%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

IRAK inhibitor 4 (trans) is the trans form of IRAK inhibitor 4. IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor.

For research use only. We do not sell to patients.

IRAK inhibitor 4 (trans) Chemical Structure

CAS No. : 2070014-89-8

Size	Price	Stock	Quantity
2 mg	USD 420	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 804	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 1280	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 2560	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 3980	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 5980	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Other Forms of IRAK inhibitor 4 (trans):

IRAK inhibitor 4 In-stock

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Biological Activity
Purity & Documentation
References
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Description

IRAK inhibitor 4 (trans) is the trans form of IRAK inhibitor 4. IRAK inhibitor 4 is an interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor.

IC₅₀ & Target

IRAK4

Molecular Weight

620.66

Formula

C₃₃H₃₅F₃N₆O₃

CAS No.

2070014-89-8

Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(C1=CC=C2C(N=C(NC3=NNC4=C3C=C(C5=CC=CC=C5OC(F)(F)F)C=C4)N2[C@@H]6CC[C@@H](O)CC6)=C1)NCCC(C)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : ≥ 38 mg/mL (61.23 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6112 mL	8.0559 mL	16.1119 mL
5 mM	0.3222 mL	1.6112 mL	3.2224 mL
10 mM	0.1611 mL	0.8056 mL	1.6112 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.02%

Select Batch:

Data Sheet (272 KB) SDS (0 KB)

COA (252 KB) LCMS (268 KB)

Handling Instructions (2659 KB)

References

[1]. Indazole derivatives as modulators of interleukin-1 receptor-associated kinase. Patent WO 2008030584 A2.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.6112 mL	8.0559 mL	16.1119 mL	40.2797 mL
	5 mM	0.3222 mL	1.6112 mL	3.2224 mL	8.0559 mL
	10 mM	0.1611 mL	0.8056 mL	1.6112 mL	4.0280 mL
	15 mM	0.1074 mL	0.5371 mL	1.0741 mL	2.6853 mL
	20 mM	0.0806 mL	0.4028 mL	0.8056 mL	2.0140 mL
	25 mM	0.0644 mL	0.3222 mL	0.6445 mL	1.6112 mL
	30 mM	0.0537 mL	0.2685 mL	0.5371 mL	1.3427 mL
	40 mM	0.0403 mL	0.2014 mL	0.4028 mL	1.0070 mL
	50 mM	0.0322 mL	0.1611 mL	0.3222 mL	0.8056 mL
	60 mM	0.0269 mL	0.1343 mL	0.2685 mL	0.6713 mL