2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Pyrroloquinoline quinone disodium salt

Pyrroloquinoline quinone disodium salt  (Synonyms: PQQ disodium salt; Methoxatin disodium salt)

Cat. No.: HY-100196A Purity: ≥98.0%
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Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function.

For research use only. We do not sell to patients.

Pyrroloquinoline quinone disodium salt Chemical Structure

Pyrroloquinoline quinone disodium salt Chemical Structure

CAS No. : 122628-50-6

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Based on 2 publication(s) in Google Scholar

Other Forms of Pyrroloquinoline quinone disodium salt:

Pyrroloquinoline quinone disodium salt Related Antibodies

Top Publications Citing Use of Products

2 Publications Citing Use of MCE Pyrroloquinoline quinone disodium salt

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Pyrroloquinoline quinone disodium salt, a redox co-factor, is an anionic, redox-cycling orthoquinone. Pyrroloquinoline quinone disodium salt is isolated from cultures of methylotropic bacteria and tissues of mammals. Pyrroloquinoline quinone disodium salt is an essential nutrient for mammals and is important for immune function[1][2].

IC50 & Target[1]

Microbial Metabolite

 

Human Endogenous Metabolite

 

In Vitro

Mouse pups born to and nursing from Pyrroloquinoline quinone disodium salt-deprived dams have a compromised immune response as well as alopecia, a hunched posture, and a susceptibility to aortic aneurysms[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Pyrroloquinoline quinone disodium salt Related Antibodies
Molecular Weight

374.17

Formula

C14H4N2Na2O8
CAS No.
Appearance

Solid

Color

Pink to red

SMILES

O=C(C(N1)=CC(C2=O)=C1C3=C(N=C(C(O[Na])=O)C=C3C(O)=O)C2=O)O[Na]
Structure Classification
Initial Source

Guinea-pig neutrophils
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 1.25 mg/mL (3.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6726 mL 13.3629 mL 26.7258 mL
5 mM --- --- ---
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 2 mg/mL (5.35 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

  • Protocol 2

    Add each solvent one by one:  0.5% CMC-Na/saline water

    Solubility: 5 mg/mL (13.36 mM); Suspended solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.6726 mL 13.3629 mL 26.7258 mL 66.8145 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Pyrroloquinoline quinone disodium salt Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pyrroloquinoline quinone disodium122628-50-6PQQ disodiumMethoxatin disodiumEndogenous Metaboliteredoxco-factoranionicmethylotropicbacteriaessentialnutrientimmunefunctionInhibitorinhibitorinhibit

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