2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Midodrine hydrochloride

Midodrine hydrochloride  (Synonyms: (±)-Midodrine hydrochloride)

Cat. No.: HY-12749A Purity: 99.49%
COA Handling Instructions

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Midodrine hydrochloride ((±)-Midodrine hydrochloride) is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension.

For research use only. We do not sell to patients.

Midodrine hydrochloride Chemical Structure

Midodrine hydrochloride Chemical Structure

CAS No. : 43218-56-0

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
 USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
5 mg USD 50 In-stock
10 mg USD 80 In-stock
25 mg USD 160 In-stock
50 mg   Get quote  
100 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Other Forms of Midodrine hydrochloride:

Midodrine hydrochloride Related Antibodies

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Description

Midodrine hydrochloride ((±)-Midodrine hydrochloride) is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension.

IC50 & Target

α adrenergic receptor

 

Clinical Trial
Molecular Weight

290.74

Formula

C12H19ClN2O4
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C(NCC(C1=CC(OC)=CC=C1OC)O)CN.[H]Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (343.95 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4395 mL 17.1975 mL 34.3950 mL
5 mM 0.6879 mL 3.4395 mL 6.8790 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.49%

COA (246 KB) HNMR (274 KB) LCMS (90 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.4395 mL 17.1975 mL 34.3950 mL 85.9875 mL
5 mM 0.6879 mL 3.4395 mL 6.8790 mL 17.1975 mL
10 mM 0.3439 mL 1.7197 mL 3.4395 mL 8.5987 mL
15 mM 0.2293 mL 1.1465 mL 2.2930 mL 5.7325 mL
20 mM 0.1720 mL 0.8599 mL 1.7197 mL 4.2994 mL
25 mM 0.1376 mL 0.6879 mL 1.3758 mL 3.4395 mL
30 mM 0.1146 mL 0.5732 mL 1.1465 mL 2.8662 mL
40 mM 0.0860 mL 0.4299 mL 0.8599 mL 2.1497 mL
50 mM 0.0688 mL 0.3439 mL 0.6879 mL 1.7197 mL
60 mM 0.0573 mL 0.2866 mL 0.5732 mL 1.4331 mL
80 mM 0.0430 mL 0.2150 mL 0.4299 mL 1.0748 mL
100 mM 0.0344 mL 0.1720 mL 0.3439 mL 0.8599 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Midodrine hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Midodrine43218-56-0(±)-MidodrineAdrenergic ReceptorBeta ReceptorInhibitorinhibitorinhibit

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