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Nylidrin hydrochloride  (Synonyms: Buphenine hydrochloride)

Cat. No.: HY-B1404 Purity: 99.89%
COA Handling Instructions

Nylidrin hydrochloride was an effective inhibitor of IgE-mediated release of histamine from passively sensitized rat peritoneal mast cells and human basophils, and of IgG1-mediated release of histamine from passively sensitized guinea pig lung slices.

For research use only. We do not sell to patients.

Nylidrin hydrochloride Chemical Structure

Nylidrin hydrochloride Chemical Structure

CAS No. : 849-55-8

Size Price Stock Quantity
Free Sample (0.1 - 0.5 mg)   Apply Now  
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
USD 86 In-stock
Solution
10 mM * 1 mL in DMSO USD 86 In-stock
Solid
100 mg USD 78 In-stock
200 mg USD 125 In-stock
500 mg USD 250 In-stock
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5 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Nylidrin hydrochloride was an effective inhibitor of IgE-mediated release of histamine from passively sensitized rat peritoneal mast cells and human basophils, and of IgG1-mediated release of histamine from passively sensitized guinea pig lung slices.

Molecular Weight

335.87

Formula

C19H26ClNO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C(NC(C)CCC1=CC=CC=C1)C)C2=CC=C(O)C=C2.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 41 mg/mL (122.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 5 mg/mL (14.89 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9773 mL 14.8867 mL 29.7734 mL
5 mM 0.5955 mL 2.9773 mL 5.9547 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.89%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 2.9773 mL 14.8867 mL 29.7734 mL 74.4336 mL
5 mM 0.5955 mL 2.9773 mL 5.9547 mL 14.8867 mL
10 mM 0.2977 mL 1.4887 mL 2.9773 mL 7.4434 mL
DMSO 15 mM 0.1985 mL 0.9924 mL 1.9849 mL 4.9622 mL
20 mM 0.1489 mL 0.7443 mL 1.4887 mL 3.7217 mL
25 mM 0.1191 mL 0.5955 mL 1.1909 mL 2.9773 mL
30 mM 0.0992 mL 0.4962 mL 0.9924 mL 2.4811 mL
40 mM 0.0744 mL 0.3722 mL 0.7443 mL 1.8608 mL
50 mM 0.0595 mL 0.2977 mL 0.5955 mL 1.4887 mL
60 mM 0.0496 mL 0.2481 mL 0.4962 mL 1.2406 mL
80 mM 0.0372 mL 0.1861 mL 0.3722 mL 0.9304 mL
100 mM 0.0298 mL 0.1489 mL 0.2977 mL 0.7443 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Nylidrin hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nylidrin hydrochloride
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