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  4. Polidocanol

Polidocanol  (Synonyms: Polyoxyethylene lauryl ether; Polyoxyethyleneglycol Dodecyl Ether)

Cat. No.: HY-B2106 Purity: ≥98.0%
COA Handling Instructions

Molarity Calculator

Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

For research use only. We do not sell to patients.

Polidocanol Chemical Structure

Polidocanol Chemical Structure

CAS No. : 9002-92-0

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500 mg USD 25 In-stock
1 g USD 40 In-stock
5 g USD 84 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Polidocanol Related Antibodies

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Description

Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

In Vivo

Polidocanol (0.5%, 1%, and 2%) results in significantly more adhesions than tetracycline, whereas the effect of diluted polidocanol is similar to that of tetracycline in rats. The higher concentrations of polidocanol, of 0.5%, 1%, and 2% are more effective than either the diluted polidocanol or tetracycline against pleurodesis[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
Formula

(C2H4O)nC12H26O
CAS No.
Appearance

<48°C Solid,>48°C Liquid

Color

Off-white to light yellow

SMILES

OCCCOCCCCCCCCCCCCC.[n]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 120 mg/mL (Infinity mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (238 KB) HNMR (226 KB)

Handling Instructions (2659 KB)
References
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Polidocanol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polidocanol9002-92-0Polyoxyethylene lauryl ether Polyoxyethyleneglycol Dodecyl EtherOthersInhibitorinhibitorinhibit

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