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SPDP (Synonyms: SPDP Crosslinker)

Cat. No.: HY-100216 Purity: >95.0%
Data Sheet SDS Handling Instructions

SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls.

For research use only. We do not sell to patients.
SPDP Chemical Structure

SPDP Chemical Structure

CAS No. : 68181-17-9

Size Price Stock Quantity
10 mM * 1 mL in DMSO $55 In-stock
10 mg $50 In-stock
50 mg $120 In-stock
100 mg $210 In-stock
200 mg $360 In-stock
500 mg $730 In-stock
1 g   Get quote  
5 g   Get quote  

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Description

SPDP is a short-chain crosslinker for amine-to-sulfhydryl conjugation via NHS-ester and pyridyldithiol reactive groups that form cleavable (reducible) disulfide bonds with cysteine sulfhydryls. equal amounts of anti-CD11c and anti-CTLA-4 Abs (in borate buffered saline; pH 8.5) were activated using SPDP .

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 3.2014 mL 16.0072 mL 32.0143 mL
5 mM 0.6403 mL 3.2014 mL 6.4029 mL
10 mM 0.3201 mL 1.6007 mL 3.2014 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

312.36

Formula

C₁₂H₁₂N₂O₄S₂

CAS No.

68181-17-9

Storage

-20°C, protect from light, stored under nitrogen

Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
SPDP
Cat. No.:
HY-100216
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