1. GPCR/G Protein
  2. Cholecystokinin Receptor

Cholecystokinin Receptor

Cholecystokinin (CCK) is a neuropeptide that affects growth rate in chickens by regulating appetite. CCK peptides exert their function by binding to two identified receptors, CCKAR and CCKBR in the GI tract and the brain, respectively, as well as in other organs. In mammals, CCK/CCKAR interactions affect a number of immunological parameters, including regulation of lymphocytes and functioning of monocytes.

CCK, also known as pancreozymin, is synthesized and secreted by enteroendocrine cells in the duodenum. The main function of CCK is to cause the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also induces drug tolerance to opioids like morphine and heroin. Cholecystokinin (CCK) has strong bioactivity in the regulation of a number of cell activities.

Cholecystokinin Receptor Related Products (3):

Cat. No. Product Name Effect Purity
  • HY-17617
    Nastorazepide Antagonist 99.78%
    Nastorazepide (Z-360) is a selective, orally available, 1,5-benzodiazepine-derivative gastrin/cholecystokinin 2 (CCK-2) receptor antagonist with potential antineoplastic activity.
  • HY-U00062
    Tarazepide Antagonist
    Tarazepide is a potent and specific CCK-A receptor antagonist.
  • HY-B2154
    Loxiglumide Antagonist >98.0%
    Loxiglumide is a cholecystokinin (CCK-1) receptor antagonist.