1. Immunology/Inflammation
  2. Interleukin Related

Interleukin Related

Interleukins are a group of cytokines (secreted proteins and signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4 T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.

Interleukin Related Related Products (14):

Cat. No. Product Name Effect Purity
  • HY-14908
    Vidofludimus Inhibitor 99.06%
    Vidofludimus(4SC-101; SC12267) is a novel immunosuppressive drug that inhibits DHODH; inhibits IL-17 secretion in vitro independently of effects on lymphocyte proliferation.
  • HY-15982
    APY0201 Inhibitor 98.56%
    APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC50=5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2; a unique small molecular IL-12/23 production inhibitor.
  • HY-15614
    SC144 Inhibitor 98.02%
    SC144 is the first-in-class orally active small-molecule gp130 inhibitor; inhibits cell growth in a panel of human ovarian cancer cell lines with IC50 values in a submicromolar range.
  • HY-15507
    VGX-1027 Inhibitor
    VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.
  • HY-17002
    Suplatast Tosilate Inhibitor 98.09%
    Suplatast tosilate(IPD 1151T) is a Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.
  • HY-16785A
    Veledimex racemate Inhibitor
    Veledimex racemate is the racemate of veledimex.
  • HY-16668
    Tyrphostin A1 Inhibitor
    Tyrphostin A1(AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.
  • HY-15898
    Y-320 Inhibitor
    Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.
  • HY-N0283
    Diacerein Inhibitor
    Diacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.
  • HY-19969
    YM-90709 Inhibitor
    YM-90709 is a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.
  • HY-15614A
    SC144 hydrochloride Inhibitor
    SC144 hydrochloride is the first-in-class orally active small-molecule gp130 inhibitor; inhibits cell growth in a panel of human ovarian cancer cell lines with IC50 values in a submicromolar range.
  • HY-B0667
    Balsalazide Inhibitor
    Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease.
  • HY-B0667A
    Balsalazide sodium hydrate Inhibitor
    Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
  • HY-N0619
    Mulberroside A Inhibitor
    Mulberroside A, the major active anti-tyrosinase compound in the root bark extract of Morus alba L. (Moraceae), is widely employed as an active ingredient in whitening cosmetics.