1. Immunology/Inflammation
  2. Interleukin Related

Interleukin Related

Interleukins are a group of cytokines (secreted proteins and signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). The function of the immune system depends in a large part on interleukins, and rare deficiencies of a number of them have been described, all featuring autoimmune diseases or immune deficiency. The majority of interleukins are synthesized by helper CD4 T lymphocytes, as well as through monocytes, macrophages, and endothelial cells. They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Interleukin receptors on astrocytes in the hippocampus are also known to be involved in the development of spatial memories in mice.

Interleukin Related Related Products (22):

Cat. No. Product Name Effect Purity
  • HY-14908
    Vidofludimus Inhibitor 99.05%
    Vidofludimus(4SC-101; SC12267) is a novel immunosuppressive drug that inhibits DHODH; inhibits IL-17 secretion in vitro independently of effects on lymphocyte proliferation.
  • HY-15614
    SC144 Inhibitor 98.02%
    SC144 is the first-in-class orally active small-molecule gp130 inhibitor; inhibits cell growth in a panel of human ovarian cancer cell lines with IC50 values in a submicromolar range.
  • HY-15982
    APY0201 Inhibitor 98.56%
    APY0201 is a potent PIKfyve inhibitor, which inhibits the conversion of PtdIns3P to PtdIns(3,5)P2 in the presence of in the presence of [33P]ATP with an IC50 of 5.2 nM.
  • HY-N0283
    Diacerein Inhibitor 98.22%
    Diacerein, a interleukin-1 beta inhibitor, is a slow-acting medicine of the class anthraquinone used to treat joint diseases.
  • HY-15507
    VGX-1027 Inhibitor 99.92%
    VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.
  • HY-101860
    GIBH-130 Inhibitor 99.82%
    GIBH-130 is an effective inhibitor of neuroinflammation.
  • HY-16785
    Veledimex Activator 99.09%
    Veledimex is an oral activator ligand for a proprietary gene therapy promoter system, and a moderate inhibitor of and substrate for CYP3A4/5.
  • HY-107390A
    AX-024 hydrochloride Inhibitor 99.29%
    AX-024 hydrochloride is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
  • HY-17002
    Suplatast Tosilate Inhibitor 98.09%
    Suplatast tosilate(IPD 1151T) is a Th2 cytokine inhibitor that attenuates IL-2, IL-5 and IL-13 production and has no effect on IFN-γ production.
  • HY-15898
    Y-320 Inhibitor 99.07%
    Y-320 is a new phenylpyrazoleanilide immunomodulator; inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM.
  • HY-N0619
    Mulberroside A Inhibitor 98.01%
    Mulberroside A, the major active anti-tyrosinase compound in the root bark extract of Morus alba L.
  • HY-B0667
    Balsalazide Inhibitor 99.20%
    Balsalazide is an anti-inflammatory drug used in the treatment of Inflammatory Bowel Disease.
  • HY-107390
    AX-024 Inhibitor >98.0%
    AX-024 is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TNFα), interferon-γ (IFN-γ), IL-10 and IL-17A.
  • HY-16785A
    Veledimex racemate
    Veledimex racemate is the racemate of veledimex.
  • HY-19969
    YM-90709 Inhibitor
    YM-90709 is a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor.
  • HY-101687
    Nosantine racemate
    Nosantine racemate is the racemate of Nosantine.
  • HY-101757
    NO-prednisolone Agonist
    NO-prednisolone is a nitric oxide (NO)-releasing derivative of Prednisolone.
  • HY-101716
    RP-54745 Inhibitor
    RP 54745 is an inhibitor of macrophage stimulation and interleukin-1 production, and a potential antirheumatic compound.
  • HY-16668
    Tyrphostin A1 Inhibitor 99.25%
    Tyrphostin A1(AG9) inhibits CD40L-stimulated IL-12 production in macrophage cultures and antigen-induced generation of Th1 cells.
  • HY-15614A
    SC144 hydrochloride Inhibitor
    SC144 hydrochloride is the first-in-class orally active small-molecule gp130 inhibitor; inhibits cell growth in a panel of human ovarian cancer cell lines with IC50 values in a submicromolar range.