Tertatolol (Synonyms: (±)-Tertatolol; Racemic Tertatolol; dl-Tertatolol)

Cat. No.: HY-U00356: FAQs
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Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.

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Tertatolol Chemical Structure

CAS No. : 83688-84-0

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α adrenergic receptor β adrenergic receptor

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5-HT₁ Receptor 5-HT₂ Receptor 5-HT₃ Receptor 5-HT₄ Receptor 5-HT₅ Receptor 5-HT₆ Receptor 5-HT₇ Receptor 5-HT Receptor

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Purity & Documentation
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Description	Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.
In Vitro	In serum-free media, tertatolol does not significantly alter the incorporation of ³H-thymidine after 28 h of incubation in human mesangial cell (HMC). In the presence of 1% serum, tertatolol significantly reduces ³H-thymidine incorporation. Tertatolol also inhibits ³H incorporation when PDGF and thrombin are used as the stimulus. Tertatolol inhibits the reduction in planar surface area of HMC induced by angiotensin II. The inhibitory effect of tertatolol on HMC proliferation is also potentiated by ritanserin and MDL 72222, 5HT2 and 5HT3 antagonists, respectively^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Tertatolol Related Antibodies
Molecular Weight	295.44
Formula	C₁₆H₂₅NO₂S
CAS No.	83688-84-0
SMILES	OC(CNC(C)(C)C)COC1=C2C(CCCS2)=CC=C1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (265 KB) Handling Instructions (2659 KB)
References	[1]. Shultz P, et al. Tertatolol: a beta-blocker with unique effects on human glomerular cell function. Cardiology. 1993;83 Suppl 1:51-6. [Content Brief]

Tertatolol Related Classifications

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tertatolol83688-84-0(±)-Tertatolol Racemic Tertatolol dl-TertatololAdrenergic Receptor5-HT ReceptorBeta ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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Tertatolol (Synonyms: (±)​-​Tertatolol; Racemic Tertatolol; dl-​Tertatolol)

Tertatolol Related Antibodies