1. Cell Cycle/DNA Damage
  2. DNA Alkylator/Crosslinker

Uramustine (Synonyms: Uracil mustard)

Cat. No.: HY-13544
Handling Instructions

Uramustine is an antineoplastic agent with of 5.1μM in K562 human leukemia cell line.

For research use only. We do not sell to patients.
Uramustine Chemical Structure

Uramustine Chemical Structure

CAS No. : 66-75-1

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO $66 In-stock
5 mg $60 In-stock
10 mg $80 In-stock
50 mg $100 In-stock
100 mg $120 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

Uramustine is an antineoplastic agent with of 5.1μM in K562 human leukemia cell line. IC50 value: 5.1 μM Target: DNA alkylator/crosslinker Uramustine is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells.

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.9667 mL 19.8334 mL 39.6668 mL
5 mM 0.7933 mL 3.9667 mL 7.9334 mL
10 mM 0.3967 mL 1.9833 mL 3.9667 mL
References
M.Wt

252.1

Formula

C₈H₁₁Cl₂N₃O₂

CAS No.

66-75-1

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 29 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Uramustine
Cat. No.:
HY-13544
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