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Signaling Pathway

Uramustine

HY-13544

(Uracil mustard)

Uramustine

Uramustine Chemical Structure

Uramustine is an antineoplastic agent with of 5.1μM in K562 human leukemia cell line.

Size Price Stock Quantity
10 mM * 1 mL in DMSO $66 In-stock
5 mg $60 In-stock
10 mg $80 In-stock
50 mg $100 In-stock
100 mg $120 In-stock
200 mg Get quote
500 mg Get quote
Size Price Stock Quantity
10 mM * 1 mL in DMSO €65 In-stock
5 mg €59 In-stock
10 mg €78 In-stock
50 mg €98 In-stock
100 mg €118 In-stock
200 mg Get quote
500 mg Get quote

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Inquiry Information
Product name: Uramustine
Cat. No.: HY-13544

Uramustine Data Sheet

  • Pdf Version Network Version

    DataSheet

Related Compound Libraries

Biological Activity of Uramustine

Uramustine is an antineoplastic agent with of 5.1μM in K562 human leukemia cell line.
IC50 value: 5.1 μM
Target: DNA alkylator/crosslinker
Uramustine is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells.

Chemical Information

M.Wt 252.1 Storage Please store the product under the recommended conditions in the Certificate of Analysis.
Formula C8H11Cl2N3O2
CAS No 66-75-1
Solvent & Solubility

DMSO:31mg/mL

Preparing Stock Solutions

1 mg 5 mg 10 mg
1 mM 3.9667 mL 19.8334 mL 39.6668 mL
5 mM 0.7933 mL 3.9667 mL 7.9334 mL
10 mM 0.3967 mL 1.9833 mL 3.9667 mL

References on Uramustine

Inhibitor Kit
  • Busulfan

    Busulfan is a bifunctional alkylating agent.

  • Calicheamicin

    Calicheamicin is a potent DNA-binding cytotoxic antibiotic.

  • Carboplatin

    Carboplatin is a chemotherapy drug by binding to DNA and interfering with the cell(acute)s repair mechanism.

  • Carmustine

    Carmustine is a cell-cycle phase nonspecific alkylating antineoplastic agent.

  • Cisplatin

    Cisplatin(CDDP) is an inorganic platinum complex, which is able to inhibit DNA synthesis by conforming DNA adducts.

  • Fotemustine

    Fotemustine (S 10036) is a nitrosourea alkylating agent approved for use in the treatment of metastasising melanoma.

  • Ifosfamide

    Ifosfamide is a nitrogen mustard alkylating agent used in the treatment of cancer.

  • Lomustine

    Lomustine (CCNU) is an alkylating nitrosourea compound used in chemotherapy.

  • Melphalan

    Melphalan(Sarcolysin; L-PAM) is a chemotherapy drug belonging to the class of nitrogen mustard alkylating agents; attaches the alkyl group to the guanine base of DNA.

  • Mitomycin C

    Mitomycin C is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells.

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