Gadodiamide hydrate

Name: Gadodiamide hydrate
Brand: MedChemExpress
SKU: HY-B0266
Rating: 4.5 (1 reviews)

Cat. No.: HY-B0266 Purity: 99.02%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Gadodiamide hydrate is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels.

For research use only. We do not sell to patients.

Gadodiamide hydrate Chemical Structure

CAS No. : 122795-43-1

Size	Price	Stock	Quantity

Free Sample (0.1 - 0.5 mg)		Apply Now
Solid + Solvent
10 mM * 1 mL in DMSO ready for reconstitution	USD 55	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 55	In-stock	Estimated Time of Arrival: December 31
Solid
100 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
500 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
1 g		Get quote
5 g		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Gadodiamide hydrate:

Gadodiamide In-stock

1 Publications Citing Use of MCE Gadodiamide hydrate

•Magn Reson Imaging. 2018 Oct 12;55:140-144. [Abstract]

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Gadodiamide hydrate is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Target: Others Gadodiamide hydrate is a gadolinium-based contrast agent used in MR imaging procedures to assist in the visualization of blood vessels. Gadodiamide hydrate is a contrast medium for cranial and spinal magnetic resonance imaging (MRI) and for general MRI of the body after intravenous administration. The product provides contrast enhancement and facilitates visualisation of abnormal structures or lesions in various parts of the body including the central nervous system (CNS). A recent review takes the question of toxicity caused by loss of gadolinium from the complex. "The challenge for nephrologists includes (a) evidence of transmetallation, such as gadolinium deposits in bone, increased urinary zinc excretion, iron-transferrin dissociation or 'spurious hypocalcemia' in exposed people" [1].

Clinical Trial

Molecular Weight

591.67

Formula

C₁₆H₂₈GdN₅O₉

CAS No.

122795-43-1

Appearance

Solid

Color

White to off-white

SMILES

CNC1=O[Gd+3]([N]2(C3)CC4)([N]5(C6)CC2)(O=C(NC)C5)([O-]C7=O)([O-]C6=O)([O-]C3=O)[N]4(C7)C1.O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (169.01 mM; Need ultrasonic)

DMSO : 50 mg/mL (84.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.6901 mL	8.4507 mL	16.9013 mL
5 mM	0.3380 mL	1.6901 mL	3.3803 mL
10 mM	0.1690 mL	0.8451 mL	1.6901 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 99.02%

Select Batch:

Data Sheet (282 KB) SDS (392 KB)

COA (263 KB) LCMS (89 KB)

Handling Instructions (2659 KB)

References

[1]. Canavese, C., et al., Gadolinium-associated nephrogenic systemic fibrosis: the need for nephrologists' awareness. J Nephrol, 2008. 21(3): p. 324-36. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	1.6901 mL	8.4507 mL	16.9013 mL	42.2533 mL
	5 mM	0.3380 mL	1.6901 mL	3.3803 mL	8.4507 mL
	10 mM	0.1690 mL	0.8451 mL	1.6901 mL	4.2253 mL
	15 mM	0.1127 mL	0.5634 mL	1.1268 mL	2.8169 mL
	20 mM	0.0845 mL	0.4225 mL	0.8451 mL	2.1127 mL
	25 mM	0.0676 mL	0.3380 mL	0.6761 mL	1.6901 mL
	30 mM	0.0563 mL	0.2817 mL	0.5634 mL	1.4084 mL
	40 mM	0.0423 mL	0.2113 mL	0.4225 mL	1.0563 mL
	50 mM	0.0338 mL	0.1690 mL	0.3380 mL	0.8451 mL
	60 mM	0.0282 mL	0.1408 mL	0.2817 mL	0.7042 mL
	80 mM	0.0211 mL	0.1056 mL	0.2113 mL	0.5282 mL
H₂O	100 mM	0.0169 mL	0.0845 mL	0.1690 mL	0.4225 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.