2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. mAChR-IN-1

mAChR-IN-1 is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM.

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mAChR-IN-1 Chemical Structure

mAChR-IN-1 Chemical Structure

CAS No. : 119391-56-9

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mAChR-IN-1 Related Antibodies

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Description

mAChR-IN-1 is a potent muscarinic cholinergic receptor (mAChR) antagonist, with an IC50 of 17 nM[1].

Molecular Weight

488.36

Formula

C23H25IN2O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C(C1CCN(CC2=CC=C(I)C=C2)CC1)(C3=CC=CC=C3)CC4)NC4=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 52 mg/mL (106.48 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0477 mL 10.2383 mL 20.4767 mL
5 mM 0.4095 mL 2.0477 mL 4.0953 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0477 mL 10.2383 mL 20.4767 mL 51.1917 mL
5 mM 0.4095 mL 2.0477 mL 4.0953 mL 10.2383 mL
10 mM 0.2048 mL 1.0238 mL 2.0477 mL 5.1192 mL
15 mM 0.1365 mL 0.6826 mL 1.3651 mL 3.4128 mL
20 mM 0.1024 mL 0.5119 mL 1.0238 mL 2.5596 mL
25 mM 0.0819 mL 0.4095 mL 0.8191 mL 2.0477 mL
30 mM 0.0683 mL 0.3413 mL 0.6826 mL 1.7064 mL
40 mM 0.0512 mL 0.2560 mL 0.5119 mL 1.2798 mL
50 mM 0.0410 mL 0.2048 mL 0.4095 mL 1.0238 mL
60 mM 0.0341 mL 0.1706 mL 0.3413 mL 0.8532 mL
80 mM 0.0256 mL 0.1280 mL 0.2560 mL 0.6399 mL
100 mM 0.0205 mL 0.1024 mL 0.2048 mL 0.5119 mL
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mAChR-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mAChR-IN-1119391-56-9mAChRMuscarinic acetylcholine receptorInhibitorinhibitorinhibit

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